EXPRESSION OF CONCERN: Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage. [PDF]
J Cereb Blood Flow Metabeuropepmc +1 more source
Use of Psychoactive Substances Before Incarceration Among Prison Inmates With Drug Abuse or Dependence: Data From the OPPIDUM Program. [PDF]
Fundam Clin PharmacolAbbas Z +6 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop +3 more
wiley +1 more source
Enrollment and Compliance in an Ecological Momentary Assessment Study of Later Life. [PDF]
Field methodsRoth AR +5 more
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Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
British Journal of Clinical Pharmacology, EarlyView.Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
The Synthesis, Metal Exchange, and Hyaluronate Functionalization of a Cationic Gallium-Based Thiosemicarbazone Anticancer Drug. [PDF]
MoleculesNing Y, Dong ML, Zhang WH, Young DJ.
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Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
British Journal of Clinical Pharmacology, EarlyView.Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
A Chimeric LBT-GFP Biosensor Exhibits Antithetical Fluorescence Responses to Ca<sup>2+</sup> and Dy<sup>3+</sup> Binding. [PDF]
ACS OmegaLi J +5 more
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Berichte zur Wissenschaftsgeschichte, EarlyView.Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley +1 more source
Correction: Atac, A.; Atak, E. The Effect of Stretching Exercises Applied to Caregivers of Children with Development Disabilities on Musculoskeletal Muscle Mobility and Respiratory Function. <i>Int. J. Environ. Res. Public Health</i> 2024, <i>21</i>, 1361. [PDF]
Int J Environ Res Public HealthAtac A, Atak E.
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