Results 281 to 290 of about 1,768,342 (381)

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

open access: yesAdvanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu   +11 more
wiley   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

open access: yesAdvanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li   +8 more
wiley   +1 more source

510 Study on quantification to measure the droplet size distribution using the method of LIF and Mie scattering

open access: bronze, 2004
Yasuyuki Nagano   +4 more
openalex   +2 more sources

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo   +10 more
wiley   +1 more source

CsPbBr3 Perovskite‐Based Heterostructures in Photocatalysis: Mechanisms, Stability, and Multifunctional Performance

open access: yesAdvanced Science, EarlyView.
This review synthesizes breakthroughs in CsPbBr3 heterostructure photocatalysis: 1) Mechanistic insights on band alignment engineering (Type‐II/Z/S‐scheme) for suppressed charge recombination; 2) Stabilization strategies via interfacial encapsulation and defect passivation overcoming hydrolysis; 3) Multifunctional design principles enabling efficient ...
Kuanxin Lv   +5 more
wiley   +1 more source

Optilume balloon dilation for radiation induced posterior urethral stenosis: a multi-institutional experience. [PDF]

open access: yesBMC Urol
Ceballos B   +13 more
europepmc   +1 more source

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy