Results 51 to 60 of about 1,768,342 (381)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

TOWARDS PREDICTING RICE LOSS DUE TO TYPHOONS IN THE PHILIPPINES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Reliable predictions of the impact of natural hazards turning into a disaster is important for better targeting humanitarian response as well as for triggering early action.
S. Boeke   +6 more
doaj   +1 more source

Meeting the challenge of change: handbook for the peer support pilot programme [PDF]

open access: yes, 2009
"This handbook sets out the aims and objectives of the Children’s Workforce Development Council’s (CWDC) peer support pilot programme and the approach on which it is based; outlines the task for those taking on a peer support role; and explains how ...

core  

Cassell and Hiremath\u27s Reference and information services: An introduction (3rd ed.) (Book Review)

open access: yes, 2017
A review of Cassell, K. A., & Hiremath, U. (2013). Reference and information services: An introduction (3rd ed.). Chicago: Neal-Schuman. 510 pp. $88.00.
Hartog, Paul
core   +1 more source

Towards a Reconfigurable Sense-and-Stimulate Neural Interface Generating Biphasic Interleaved Stimulus [PDF]

open access: yes, 2007
Published ...
Constandinou, T G   +4 more
core   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Extraction of Phenolic Compounds from Cherry Seeds: A Preliminary Study

open access: yesAgronomy, 2022
Agri-food waste has proved to be a valuable bioresource that can be used to obtain a variety of valuable materials, ingredients and chemicals. The optimum conditions for extracting bioactive compounds from sweet cherry seeds (SCS) with different solvents
Yuliya Dulyanska   +11 more
doaj   +1 more source

Time trends and predictors of gout remission over six years

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah   +5 more
wiley   +1 more source

Maritime pine land use environmental impact evolution in the context of life cycle assessment

open access: yesOpen Agriculture, 2022
Between 2005 and 2015, the forest area occupied by maritime pine trees in Continental Portugal decreased by about 10.6%, and the existing volume decreased by about 18.4% mainly due to fires and pests (e.g., nematode) that occurred during this period. The
Ferreira José   +3 more
doaj   +1 more source

Development of a personalized visualization and analysis tool to improve clinical care in complex multisystem diseases with application to scleroderma

open access: yesArthritis Care &Research, Accepted Article.
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim   +18 more
wiley   +1 more source

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