Results 31 to 40 of about 24,557 (225)

Enhancing Enzyme Activity With Mutation Combinations Guided by Few‐Shot Learning and Causal Inference

open access: yesAngewandte Chemie International Edition, EarlyView.
We present an integrated workflow that predicts activity‐enhancing mutation combinations from minimal experimental data. By proposing in vivo unit yield (yield/expression) as a surrogate for kcat/Km through causal inference, and visualizing local activity landscape, it effectively guides product yield improvement. ABSTRACT Designing enzyme sequences to
Lin Guo   +15 more
wiley   +1 more source

Fish Sidestream-Derived Protein Hydrolysates Suppress DSS-Induced Colitis by Modulating Intestinal Inflammation in Mice

open access: yesMarine Drugs, 2021
Inflammatory bowel disease is characterized by extensive intestinal inflammation, and therapies against the disease target suppression of the inflammatory cascade. Nutrition has been closely linked to the development and suppression of inflammatory bowel
Maria G. Daskalaki   +10 more
doaj   +1 more source

Can prisons move people into better jobs? A look at correctional vocational training programs and sectoral employment outcomes

open access: yesCriminology, EarlyView.
Abstract Three‐quarters of US prisons offer vocational training programs, which aim to place trainees in middle‐skills jobs in specific occupational sectors post‐release. These middle‐skills jobs may more effectively reduce recidivism than the jobs that normally characterize the labor market experience of the formerly incarcerated, yet whether ...
Britte van Tiem
wiley   +1 more source

Block Card 5141 Kitchener Drive [PDF]

open access: yes, 1990
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 5141 Kitchener Drive (Toledo, Ohio) | Dwelling ...
Lucas County (Ohio). Auditor's Office
core  

Blinatumomab for treatment of children with acute lymphoblastic leukaemia in Hong Kong: A cost‐effectiveness analysis

open access: yesBritish Journal of Haematology, EarlyView.
Summary To assess the cost‐effectiveness of blinatumomab plus chemotherapy for paediatric patients from Hong Kong public healthcare provider's perspective, a 10‐year Markov model was designed to simulate outcomes in paediatric patients with newly diagnosed standard‐risk B‐cell ALL at: (1) average risk and (2) high risk of relapse.
Mingjun Rui   +7 more
wiley   +1 more source

Block Card 5141 Egger Road [PDF]

open access: yes, 1990
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: 5141 Egger Road (Toledo, Ohio) | Dwelling | Westhaven First ...
Lucas County (Ohio). Auditor's Office
core  

Optimal time-decay rates of the Keller–Segel system coupled to compressible Navier–Stokes equation in three dimensions

open access: yesBoundary Value Problems, 2022
Recently, Hattori–Lagha established the global existence and asymptotic behavior of the solutions for a three-dimensional compressible chemotaxis system with chemoattractant and repellent (Hattori and Lagha in Discrete Contin. Dyn. Syst. 41(11):5141–5164,
Yuting Guo, Rui Sun, Weiwei Wang
doaj   +1 more source

Preschool Duration, Family Background and Long‐Term Outcomes: Evidence From the Expansion of École Maternelle in France

open access: yesOxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT This paper analyses the long‐term effects of preschool education in France. We focus on the effect of preschool duration on educational attainment and labour market earnings in adulthood. Building on an old tradition of free and universal pre‐primary education, France implemented in the late 1960s a large‐scale expansion of preschooling ...
Francesco Andreoli   +2 more
wiley   +1 more source

Block Card 5141 Golden Road [PDF]

open access: yes, 1990
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 5141 Golden Road (Toledo, Ohio) | Dwelling ...
Lucas County (Ohio). Auditor's Office
core  

Sobre el concepto de América Latina¿Invención francesa?

open access: yesCahiers d’Études Romanes, 2016
Le concept d’Amérique latine naît comme un terme promu par des intérêts économiques et politiques de l’empire français de Napoléon III, ainsi que par la nécessité d’imposer la France comme un contrepoids face à l’influence grandissante des États-Unis ...
Rubén Torres Martínez
doaj   +1 more source

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