Results 131 to 140 of about 1,690,007 (382)

Soluble Guanylate Cyclase Redox State Under Hypoxia or Hypoxia/Reoxygenation in Isolated Monkey Coronary Arteries

open access: yesJournal of Pharmacological Sciences, 2014
.: Hypoxia or hypoxia/reoxygenation impairs nitric oxide (NO)-mediated relaxation through the increase in superoxide generation in monkey coronary arteries.
Masashi Tawa   +5 more
doaj  

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

open access: yesAdvanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai   +9 more
wiley   +1 more source

Analysis of Mechanisms of Mandible Fractures by Lateral Impact: A Biomechanical Approach Using Finite Element Models

open access: yesApplied Sciences
Background/Aim: The purpose of this study was to reproduce a lateral fall using a computer simulation model and to clarify the circumstances of mandible fracture caused by a lateral impact.
Takahiro Tomioka   +7 more
doaj   +1 more source

Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling

open access: yesAdvanced Functional Materials, EarlyView.
Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta   +2 more
wiley   +1 more source

Short-period 520-km observation of the 520 km discontinuity in northern Eurasia.

open access: yes, 1997
Short-period three-component recordings of the seismic wave field of peaceful nuclear explosions (PNEs) along several long-range profiles in northern Eurasia are analyzed to study the structure of the upper mantle. We use the date to search for evidence of the disputed 520 km discontinuity in the mantle transition zone.
Ryberg, T.   +3 more
openaire   +2 more sources

Hyperlalia: A Right Cerebral Hemisphere Syndrome

open access: yesBehavioural Neurology, 1990
We describe a new right hemispheric behavioural syndrome for which we propose the name “hyperlalia”. In a typical case an apparently unconcerned and expressionless patient is easily prompted to remarkable volubility with a content which is loose and ...
Atsushi Yamadori   +6 more
doaj   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song   +8 more
wiley   +1 more source

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