Results 41 to 50 of about 246,229 (319)

Problem-Solving Exercise for Undergraduate Students Involving the Japanese Fermented Food Natto

open access: yesJournal of Microbiology & Biology Education, 2019
Natto is a traditional Japanese food made from soybeans fermented by Bacillus subtilis natto. Because natto is high in protein and contains healthful bacteria, dieticians and producers have campaigned for higher consumption of natto in areas such as ...
Yoko Yoshiyama, Jun Shima, Toru Fushiki
doaj   +1 more source

Current Overview of Osteogenesis Imperfecta

open access: yesMedicina, 2021
Osteogenesis imperfecta (OI), or brittle bone disease, is a heterogeneous disorder characterised by bone fragility, multiple fractures, bone deformity, and short stature.
Mari Deguchi   +5 more
doaj   +1 more source

Screening in (2+1)D pure gauge theory at high temperatures [PDF]

open access: yesNucl.Phys.Proc.Suppl.42:520-522,1995, 1995
We compute heavy quark potentials in pure gauge $SU(3)$ at high temperatures in $2+1$ dimensions and confront them with expectations emerging from perturbative calculations.
arxiv   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Red face may be a specific sign of SARS-CoV-2 alpha variant

open access: yesIDCases, 2021
Japan is currently suffering the fourth wave of the COVID-19 pandemic, with the dominant type being SARS-CoV-2 alpha variant. Patients with COVID-19 variant types show more aggressive symptoms.
Aya Nakaya   +16 more
doaj  

Efficient single-pass third-harmonic generation at 520 nm for pumping doubly-resonant OPO [PDF]

open access: yes, 2017
A ~545 mW single-frequency tunable 520 nm green laser has been demonstrated using a periodically-poled potassium titanyl phosphate (PPKTP) bulk crystal based on single-pass third-harmonic generation (THG) of a 1560 nm laser via single-pass second-harmonic generation (SHG) followed by single-pass sum-frequency generation (SFG).
arxiv   +1 more source

SU(3) vortex-like configurations in the maximal center gauge [PDF]

open access: yesNucl.Phys.Proc.Suppl. 83 (2000) 518-520, 1999
A new algorithm for fixing the gauge to (direct) maximal center gauge in SU(N) lattice gauge theory is presented. We check how this method works on SU(3) configurations which are vortex-like, and show how these configurations look like when center projected.
arxiv   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Hsa_circ_0088212-mediated miR-520 h/APOA1 axis inhibits osteosarcoma progression

open access: yesTranslational Oncology, 2021
Background: It has been known for decades that circRNAs are deregulated in cancer. Here, we characterized the role and underlying mechanism of circ_0088212 in osteosarcoma.
Feng Liu   +3 more
doaj  

Niclosamide and its derivative DK‐520 inhibit RANKL‐induced osteoclastogenesis

open access: yesFEBS Open Bio, 2020
Niclosamide is a potent inhibitor of osteoclastogenesis and bone remodeling. DK‐520 is an acyl derivative of Niclosamide and significantly increased both the plasma concentration and the duration of exposure of Niclosamide when dosed orally.
Yurui Jiao   +7 more
doaj   +1 more source

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