Results 61 to 70 of about 1,748,964 (382)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Bleeding anorectal varices treated by a direct puncture approach through the greater sciatic foramen: The utility of a steerable microcatheter for reverse catheterization

Radiology Case Reports, 2022
Bleeding is less common from anorectal varices than from esophageal varices, but it is potentially life-threatening. Here, we present a case of a woman in her 70s with critical hemorrhage from anorectal varices.
Shohei Chatani, MD, Kokichi Seki, MD, Akinaga Sonoda, MD, PhD, Yoko Murakami, MD, PhD, Yuki Tomozawa, MD, PhD, Takehide Fujimoto, MD, PhD, Akira Andoh, MD, PhD, Yoshiyuki Watanabe, MD, PhD   +7 more
doaj   +1 more source

Re‐evaluation of aluminium sulphates (E 520–523) and sodium aluminium phosphate (E 541) as food additives

EFSA journal. European Food Safety Authority, 2018
The Panel on Food Additives and Nutrient Sources added to Food (ANS) provided a scientific opinion re‐evaluating the safety of aluminium sulphates (E 520–523) and sodium aluminium phosphate, acidic (E 541) as food additives.
M. Younes, P. Aggett, F. Aguilar, Riccardo Crebelli, B. Dusemund, M. Filipič, M. Frutos, P. Galtier, D. Gott, U. Gundert-Remy, G. Kuhnle, C. Lambré, J. Leblanc, I. T. Lillegaard, P. Moldéus, A. Mortensen, A. Oskarsson, I. Stanković, I. Waalkens-Berendsen, M. Wright, A. di Domenico, Henk van Loveren, A. Giarola, Z. Horváth, F. Lodi, A. Tard, R. Woutersen   +26 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Opportunities and risks of an integrated academic support : [Vortrag ; Tagung] "Integration of Information Services into University Infrastructures" - 7th Frankfurt Symposium: 12.10. - 13.10.2007 [PDF]

, 2007
In the year 2000 the Deutsche Initiative für Netzwerkinformation (DINI) / German Coalition of Network Information was founded: 10 theses "Changes in information infrastructure – challenges to universities and their information and communications ...
Degkwitz, Andreas
core  

Size-dependent fine-structure splitting in self-organized InAs/GaAs quantum dots [PDF]

, 2005
A systematic variation of the exciton fine-structure splitting with quantum dot size in single InAs/GaAs quantum dots grown by metal-organic chemical vapor deposition is observed.
A. Schliwa, D. Bimberg, K. Pötschke, R. Seguin, S. Adachi, S. Rodt, U. W. Pohl   +6 more
core   +1 more source

Niclosamide and its derivative DK‐520 inhibit RANKL‐induced osteoclastogenesis

FEBS Open Bio, 2020
Niclosamide is a potent inhibitor of osteoclastogenesis and bone remodeling. DK‐520 is an acyl derivative of Niclosamide and significantly increased both the plasma concentration and the duration of exposure of Niclosamide when dosed orally.
Yurui Jiao, Chenglong Chen, Xijian Hu, Xu Feng, Zhenqi Shi, Jie Cao, Qing Li, Yikun Zhu   +7 more
doaj   +1 more source

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source