Results 41 to 50 of about 1,736,707 (281)

Problem-Solving Exercise for Undergraduate Students Involving the Japanese Fermented Food Natto

open access: yesJournal of Microbiology & Biology Education, 2019
Natto is a traditional Japanese food made from soybeans fermented by Bacillus subtilis natto. Because natto is high in protein and contains healthful bacteria, dieticians and producers have campaigned for higher consumption of natto in areas such as ...
Yoko Yoshiyama, Jun Shima, Toru Fushiki
doaj   +1 more source

Bleeding anorectal varices treated by a direct puncture approach through the greater sciatic foramen: The utility of a steerable microcatheter for reverse catheterization

open access: yesRadiology Case Reports, 2022
Bleeding is less common from anorectal varices than from esophageal varices, but it is potentially life-threatening. Here, we present a case of a woman in her 70s with critical hemorrhage from anorectal varices.
Shohei Chatani, MD   +7 more
doaj   +1 more source

Book Review [PDF]

open access: yes, 1992
Reviews of the following books: K. S. SHRADER-FRECHETTE, Risk AND RATIONALITY (U. California Press 1991) [312 pp.] Index of Names, Index of Subjects, Notes. CIP 91-3294; ISBN 0-520-07287-1 (Cloth $39.95); ISBN 0-520-07289-8 (Pbk. $15.95). [2120 Berkeley
Gibbons, Hugh H.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Digital Town Hall [PDF]

open access: yes, 2002
Presents findings from a survey of 520 locally elected officials. Explores to what extent they have embraced the Internet as part of their official lives and the effect that communication with constituents via email has had on community ...
Elena Larsen, Lee Rainie
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Opportunities and risks of an integrated academic support : [Vortrag ; Tagung] "Integration of Information Services into University Infrastructures" - 7th Frankfurt Symposium: 12.10. - 13.10.2007 [PDF]

open access: yes, 2007
In the year 2000 the Deutsche Initiative für Netzwerkinformation (DINI) / German Coalition of Network Information was founded: 10 theses "Changes in information infrastructure – challenges to universities and their information and communications ...
Degkwitz, Andreas
core  

Applying MOG to lensing: Einstein rings, Abell 520 and the Bullet Cluster

open access: yes, 2018
We investigate gravitational lensing in the context of the MOG modified theory of gravity. Using a formulation of the theory with no adjustable or fitted parameters, we present the MOG equations of motion for slow, nonrelativistic test particles and for ...
Moffat, J. W., Rahvar, S., Toth, V. T.
core   +2 more sources

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