Results 71 to 80 of about 169,443 (265)

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source

A Millimeter‐Scale Implantable Magneto–Mechano–Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves

Advanced Science, EarlyView.
We report a fully wireless, circuit‐free neural stimulator built on a millimetric magneto‐mechano‐electric (MME) cantilever transducer (3 × 10 × 5 mm) with a barium titanate (BTO) piezoelectric ceramic core. Under low‐frequency alternating magnetic fields, the MME cantilever mechanically oscillates, inducing stress on the BTO element and thereby ...
Yijing Wang, Jingyu Tian, Zhe Xu, Cuiling Zhang, Jingen Wu, Ming Liu, Zhilu Ye, Xiaohui Zhang   +7 more
wiley   +1 more source

Pressure‐Driven Phase Transition Unlocking Unique Eu2+ Luminescence in Li2SrSiO4 for Optical Sensing and White‐LEDs

Advanced Science, EarlyView.
This study demonstrates, for the first time, the use of a large‐format high‐pressure press to modify synthesized Li2SrSiO4:Eu2+,Cs+ phosphors after its preparation. The pressure treatment results in the formation of new materials with distinctive optical properties, opening pathways for the development of advanced LED devices and high‐performance ...
Przemysław Woźny, Peng Du, Teng Zheng, Junpeng Xue, Liang Peng, Shuailing Ma, Szymon Sobczak, Victor Lavín, Tian Cui, Marcin Runowski   +9 more
wiley   +1 more source

A potent Lassa virus antiviral targets an arenavirus virulence determinant.

PLoS Pathogens, 2018
Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a ...
Ikenna G Madu, Megan Files, Dima N Gharaibeh, Amy L Moore, Kie-Hoon Jung, Brian B Gowen, Dongcheng Dai, Kevin F Jones, Shanthakumar R Tyavanagimatt, James R Burgeson, Marcus J Korth, Kristin M Bedard, Shawn P Iadonato, Sean M Amberg   +13 more
doaj   +1 more source

Bias‐Tunable Two‐Terminal Organic Photodetector for Intelligent Imaging

Advanced Science, EarlyView.
A vertically stacked two‐terminal photodetector with a symmetric donor–acceptor–donor trilayer active exhibits reconfigurable photoresponse with bias‐tunable magnitude and polarity, together with sub‐millisecond response speed and a wide tunable output window.
Sangin Hahn, Sanghoon Park, Seunghyup Yoo   +2 more
wiley   +1 more source

Mechanistic Understanding of Protein–MOF Integration Through Surfactant‐Driven Interfacial Design

Advanced Science, EarlyView.
This study reveals how surfactant‐driven interfacial design governs the assembly and stability of protein@MOF composites. Using lipid‐based nonionic surfactants, we modulate protein–MOF interactions to improve encapsulation efficiency, MOF crystallization, and catalytic performance.
Ehsan Rashidniyaghi, Mohammad Khavani, Carlie Coerver, Ruibin Liang, Raheleh Ravanfar   +4 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Indigo Carmine Binding to Cu(II) in Aqueous Solution and Solid State: Full Structural Characterization Using NMR, FTIR and UV/Vis Spectroscopies and DFT Calculations

Molecules
The food industry uses indigo carmine (IC) extensively as a blue colorant to make processed food for young children and the general population more attractive.
Sofia Braz, Licínia L. G. Justino, M. Luísa Ramos, Rui Fausto   +3 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women

BJS (British Journal of Surgery), EarlyView., 2020
This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani, K. Chiuri, J. Broggio, G. Reeves, I. Barnes   +4 more
wiley   +1 more source