Results 181 to 190 of about 1,527,120 (330)

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Uncovering GSTK1 and PTGER3 as biomarkers for breast cancer prognosis through comprehensive analyses. [PDF]

Discov Oncol
Tan L, Xiang J, Lu Y, Zhong X.
europepmc   +1 more source

Ethnic and Social Barriers to Cooperation: Experiments Studying the Extent and Nature of Discrimination in Urban Peru [PDF]

This paper presents a series of experiments on discrimination in urban Lima, Peru. The experiments exploit degrees of information on performance as a way to assess how personal characteristics affect how people sort into groups, and the results show that
Marco Castillo, Máximo Torero, Ragan Petrie   +2 more
core  

Effects of sodium–glucose co‐transporter inhibitors on individual clinical endpoints and quality of life

ESC Heart Failure, Volume 12, Issue 2, Page 1271-1282, April 2025.
Effects of SGLTi on Individual Clinical Endpoints and Quality‐of‐Life: outcome from randomized data. Abstract Aims Sodium–glucose co‐transporter inhibitors (SGLTis) have cardiovascular protective effects. We aimed to assess the effects of SGLTis on individual hard clinical endpoints and quality of life (QoL) in patients with cardiovascular risk factors.
Jia Liao, Yang Chen, Zhiyu Ling, Helmut Pürerfellner, Martin Martinek, Michael Derndorfer, Johannes Niel, Ramin Ebrahimi, Matthias Heukäufer, Sarah Janschel, Davide Di Vece, Klaus Empen, Astrid Hummel, Bishwas Chamling, Piotr Futyma, Fahim Ebrahimi, Márcio G. Kiuchi, Shaowen Liu, Yuehui Yin, Alexandra Schratter, Willem‐Jan Acou, Philipp Sommer, Boris Schmidt, Julian K. R. Chun, Christian Meyer, Marcus Dörr, Christian Templin, Shaojie Chen   +27 more
wiley   +1 more source

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Oxidative Stress-Related Serum Extracellular Vesicle miRNAs Indicate Symptom Severity and Cognitive Decline in Parkinson's Disease. [PDF]

J Neurochem
Belickienė V, Pranckevičienė A, Radžiūnas A, Strigauskaitė A, Laucius O, Vaitkienė P.   +5 more
europepmc   +1 more source

Stigma, attitude, and knowledge of epilepsy in Italy: A survey on 1159 subjects

Epilepsia Open, EarlyView.
Abstract Objective Stigma remains a major determinant of impaired quality of life (QoL) in people with epilepsy (PwE). We aimed to investigate perceptions of epilepsy‐related stigma in the Italian general population, assess knowledge of epilepsy and seizure first aid, and identify factors associated with stigmatizing attitudes.
Marina Romozzi, Federico Tosto, Raffaele Turano, Lapo Sbrenna, Davide Chiffi, Flavia Bianchi, Vincenzo Trigila, Catello Vollono, Giovanni Assenza, Mario Tombini, Paolo Calabresi, Sonia Di Tella, Luigi Francesco Iannone   +12 more
wiley   +1 more source

Local variations in L/M ratio influence the detection and color naming of small spots. [PDF]

J Vis
Greene MJ, Pandiyan VP, Sabesan R, Tuten WS.   +3 more
europepmc   +1 more source

Age‐Related Trends in Eating‐Pathology Symptoms Among Sexual Minority Adults

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To examine how eating‐disorder symptoms vary by chronological age and sexual orientation in sexual minority adults. Method Cross‐sectional data came from 2062 cisgender sexual minority participants (925 gay men, 573 lesbian women, 116 bi+ men, 448 bi+ women; age = 47.8 years, range = 18–96).
Jason M. Nagata, Christopher D. Otmar, Char Potes, Ken Murakami, Jason M. Lavender, Emilio J. Compte, Tiffany A. Brown, Kelsie T. Forbush, Annesa Flentje, Micah E. Lubensky, Juno Obedin‐Maliver, Mitchell R. Lunn   +11 more
wiley   +1 more source

Author Correction: Impact of commonly administered drugs on the progression of spinal cord injury: a systematic review. [PDF]

Commun Med (Lond)
Bourguignon L, Lukas LP, Kondiles BR, Tong B, Lee JJ, Gomes T, Tetzlaff W, Kramer JLK, Walter M, Jutzeler CR.   +9 more
europepmc   +1 more source