EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren +15 more
wiley +1 more source
SphK1 Suppresses Human Dental Pulp Stem Cell Apoptosis by Promoting Glycolysis Under Simulated Microgravity. [PDF]
Che J +10 more
europepmc +1 more source
ABSTRACT Carbon dioxide capture, utilization, and storage (CCUS) is a potential key to mitigating anthropogenic CO2 emissions and associated impacts on global climate change. Successful CCUS deployment hinges on both technological advancements and public support.
Ting Xiao +6 more
wiley +1 more source
m5C modification of LINC01082 inhibits osteosarcoma progression by modulating the miR-543-TNRC6A axis. [PDF]
Hu Y +8 more
europepmc +1 more source
Spin‐Crossover Modulated Luminescence in Materials and Molecular Complexes
The synergistic coupling of spin‐crossover and luminescent properties holds great promise for the development of multifunctional and stimuli‐responsive molecular materials. This contribution provides a comprehensive overview of the field, surveying the possible coupling mechanisms, the various synthetic strategies and their potential applicability, as ...
Charlotte Egger, Claude Piguet
wiley +1 more source
Autophagy-dependent secretion of ENO1 mediates chemoresistance of glioblastoma and tumor microenvironment remodeling. [PDF]
Xie Q +9 more
europepmc +1 more source
What's New? Inclusion criteria for lung cancer screening (LCS) maintain cost control by focusing resources on select high‐risk groups. However, eligible individuals are inherently dissimilar in risk profile and demographics, potentially impacting LCS effectiveness and uptake.
María Olivia Cabrera +7 more
wiley +1 more source
Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation
What's New? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li +7 more
wiley +1 more source
Serum MicroRNA signatures associated with hypertrophic callus formation in polytrauma patients with traumatic brain injury. [PDF]
Lettner T +9 more
europepmc +1 more source
Incidence and risk factors for postplacental intrauterine device expulsion in a Brazilian hospital
Abstract Objective This study assessed the incidence of and risk factors associated with expulsion of copper intrauterine devices inserted in the immediate postpartum period at a public hospital in Brazil. Methods This retrospective cohort study included women who had a copper intrauterine device (IUD) inserted immediately after delivery at a teaching ...
Silvana A. Giovanelli +2 more
wiley +1 more source

