Results 111 to 120 of about 17,983,967 (290)
Vestiges of the history of popular science [Essay Review] [PDF]
, 1995 Robert Chambers, Vestiges of the Natural History of Creation and Other Evolutionary Writings, ed. James A. Secord. Chicago: University of Chicago Press. 1994. Pp. xlviii, vi, 390, viii, 254. US$ 19.95 PB.
Topham, J.R.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
On Holiday! Policy and provision for disabled children and their families [PDF]
, 2007 This summary describes some findings from the On Holiday! study, carried out by the Thomas Coram Research Unit between 2004 and 2006 and funded by DfES.
Knight, A +3 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
BEST AGERS IN THE BALTIC SEA REGION – A QUALITATIVE STUDY OF EMPLOYERS’ ATTITUDES
Research on Enterprise in Modern Economy Theory and Practice, 2012 Celem artykułu jest próba oceny wpływu zmian demograficznych na zachowania przedsiębiorstw w sześciu państwach Regionu Morza Bałtyckiego: Danii, Niemczech, Łotwy, Litwy, Polski i Szwecji.
Jonas Meixner
doaj
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Beyond denomination: The relationship between religion and family planning in rural Malawi [PDF]
Despite the centrality of religion and fertility to life in rural Africa, the relationship between the two remains poorly understood. The study presented here uses unique integrated individual- and congregational-level data from rural Malawi to examine ...
Jenny Trinitapoli, Sara Yeatman
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Encyclopedia of Religious and Spiritual Development (Review Article) [PDF]
, 2007 This is a large volume with around 300 entries and 130 contributors, mostly from the USA. The editors are child developmental psychologists. ‘Spiritual development’ is taken to be ‘aboutbecoming a whole person, someone who stands for something that ...
Bigger, Stephen
core +1 more source