Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Association between preoperative E/e' and early left ventricular systolic recovery after coronary artery bypass grafting. [PDF]
Choi J, Kim HK, Kang JK.
europepmc +1 more source
15 Der Spielmann (Herbert Zagler) [02:03] (KUG KD 55)
Text: Bruno Ertler Komposition: Herbert Zagler Interpret*innen: Birgit Stöckler (Sopran), Maria Lerchenberger (Tenor), Petar Karagenov (Klavier), Christoph Hammer (Geige), Tom Sol (Sprecher), Harald Haslmayr (Moderator) Album: Bruno Ertler "Ewigkeiten ...
core
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Lipoprotein(a) and residual cardiovascular risks in Japanese patients with coronary artery disease who achieve guideline-recommended low-density lipoprotein cholesterol goals. [PDF]
Kataoka Y +17 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Burden, Risk Factors, and Temporal Trends of Ovarian Cancer in Postmenopausal Women Aged 55 Years and Older: A Comparative Analysis in India, China, and the United States Based on the Global Burden of Disease Study 2023. [PDF]
Wei T +8 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Performance Evaluation of Lipopeptide-Enhanced Petroleum Sulfonate Binary Flooding System. [PDF]
Zhang Y +10 more
europepmc +1 more source

