Results 11 to 20 of about 484,396 (367)

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó   +16 more
wiley   +1 more source

Estimation of Radial Basis Function Network Centers via Information Forces

Entropy, 2022
The determination of The Radial Basis Function Network centers is an open problem. This work determines the cluster centers by a proposed gradient algorithm, using the information forces acting on each data point.
Edilson Sousa Júnior, Antônio Freitas, Ricardo Rabelo, Welflen Santos   +3 more
doaj   +1 more source

Discovery of Levesquamide B through Global Natural Product Social Molecular Networking

Molecules, 2022
Levesquamide A is an isothiazolinone-containing anti-tubercular natural product isolated from Streptomyces sp. RKND-216. Through the use of Global Natural Product Social Molecular Networking (GNPS), additional members of the levesquamide family were ...
Mary M. LeClair, Zacharie A. Maw, Alyssa L. Grunwald, Joshua R. Kelly, Bradley A. Haltli, Russell G. Kerr, Christopher Cartmell   +6 more
doaj   +1 more source

miR-550-1 functions as a tumor suppressor in acute myeloid leukemia via the hippo signaling pathway

International Journal on Biological Sciences, 2020
MicroRNAs (miRNAs) and N6-methyladenosine (m6A) are known to serve as key regulators of acute myeloid leukemia (AML). Our previous microarray analysis indicated miR-550-1 was significantly downregulated in AML.
Chao Hu, Meng-xia Yu, Chenying Li, Yungui Wang, Xia Li, Bryan Ulrich, R. Su, Lei Dong, Hengyou Weng, Huilin Huang, Xi Jiang, Jianjun Chen, Jie Jin   +12 more
semanticscholar   +1 more source

Digital Light Processing of 2D Lattice Composites for Tunable Self‐Sensing and Mechanical Performance

Advanced Engineering Materials, EarlyView., 2023
The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi, Mohammed Ayaz Uddin, Andreas Schiffer, Shanmugam Kumar   +3 more
wiley   +1 more source

Inhibitory effects of the JAK inhibitor CP690,550 on human CD4⁺ T lymphocyte cytokine production

BMC Immunology, 2011
Background The new JAK3 inhibitor, CP690,550, has shown efficacy in the treatment of rheumatoid arthritis. The present study was undertaken to assess the effects of CP690,550 on cytokine production and cellular signaling in human CD4+ T cells.
Yamasaki Satoshi, Aiba Yoshihiro, Jiuchi Yuka, Maeda Yumi, Komori Atsumasa, Koga Tomohiro, Izumi Yasumori, Miyashita Taiichiro, Migita Kiyoshi, Kawakami Atsushi, Nakamura Minoru, Ishibashi Hiromi   +11 more
doaj   +1 more source

Global Validation of MODIS C6 and C6.1 Merged Aerosol Products over Diverse Vegetated Surfaces

Remote Sensing, 2018
In this study, the MODerate resolution Imaging Spectroradiometer (MODIS) Collections 6 and 6.1 merged Dark Target (DT) and Deep Blue (DB) aerosol products (DTBC6 and DTBC6.1) at 0.55 µm were validated from 2004–2014 against Aerosol Robotic Network ...
Muhammad Bilal, Majid Nazeer, Zhongfeng Qiu, Xiaoli Ding, Jing Wei   +4 more
doaj   +1 more source

Coherent Control of Defect Spins in Silicon Carbide above 550 K [PDF]

Physical Review Applied, 2018
Great efforts have been made to the investigation of defects in silicon carbide for their attractive optical and spin properties. However, most of the researches are implemented at low and room temperature.
Fei-Fei Yan, Jun-Feng Wang, Qiang Li, Ze-Di Cheng, Jinming Cui, Wen-Zheng Liu, Jin-Shi Xu, Chuan‐Feng Li, G. Guo   +8 more
semanticscholar   +1 more source

Cryolipolysis on More than One Body Area Increases Lipid Peroxidation without Changing Lipid Profile and Inflammatory Markers

Biology, 2022
In the present study, the effects of cryolipolysis on one and multiple body areas, assessing body composition, lipid profile and peroxidation and inflammatory markers were investigated.
Antônio Daniel Saraiva da Costa, Amanda Suellenn da Silva Santos Oliveira, Ana Karolinne da Silva Brito, Lays Arnaud Rosal Lopes, Maísa Guimarães Silva Primo, Ana Lina de Carvalho Cunha Sales, Marcos Antônio Pereira dos Santos, Nara Vanessa dos Anjos Barros, Oséas Florêncio de Moura-Filho, Jaynara Keylla Moreira da Silva, Edwiges Ita de Miranda Moura, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Maria do Carmo de Carvalho e Martins   +14 more
doaj   +1 more source

Complicações em 550 cirurgias consecutivas de implante coclear Surgical complications in 550 consecutive cochlear implantation

Brazilian Journal of Otorhinolaryngology, 2012
A cirurgia de implante coclear (IC) é método seguro e factível de restaurar audição em pacientes com surdez grave a profunda. OBJETIVO: Descrever complicações do IC.
Rubens Brito, Tatiana Alves Monteiro, Aquiles Figueiredo Leal, Robinson Koji Tsuji, Mariana Hausen Pinna, Ricardo Ferreira Bento   +5 more
doaj   +1 more source