Results 21 to 30 of about 2,277,654 (386)

miR-550-1 functions as a tumor suppressor in acute myeloid leukemia via the hippo signaling pathway

International Journal on Biological Sciences, 2020
MicroRNAs (miRNAs) and N6-methyladenosine (m6A) are known to serve as key regulators of acute myeloid leukemia (AML). Our previous microarray analysis indicated miR-550-1 was significantly downregulated in AML.
Chao Hu, Meng-xia Yu, Chenying Li, Yungui Wang, Xia Li, Bryan Ulrich, R. Su, Lei Dong, Hengyou Weng, Huilin Huang, Xi Jiang, Jianjun Chen, Jie Jin   +12 more
semanticscholar   +1 more source

Discovery of Levesquamide B through Global Natural Product Social Molecular Networking

Molecules, 2022
Levesquamide A is an isothiazolinone-containing anti-tubercular natural product isolated from Streptomyces sp. RKND-216. Through the use of Global Natural Product Social Molecular Networking (GNPS), additional members of the levesquamide family were ...
Mary M. LeClair, Zacharie A. Maw, Alyssa L. Grunwald, Joshua R. Kelly, Bradley A. Haltli, Russell G. Kerr, Christopher Cartmell   +6 more
doaj   +1 more source

Inhibitory effects of the JAK inhibitor CP690,550 on human CD4⁺ T lymphocyte cytokine production

BMC Immunology, 2011
Background The new JAK3 inhibitor, CP690,550, has shown efficacy in the treatment of rheumatoid arthritis. The present study was undertaken to assess the effects of CP690,550 on cytokine production and cellular signaling in human CD4+ T cells.
Yamasaki Satoshi, Aiba Yoshihiro, Jiuchi Yuka, Maeda Yumi, Komori Atsumasa, Koga Tomohiro, Izumi Yasumori, Miyashita Taiichiro, Migita Kiyoshi, Kawakami Atsushi, Nakamura Minoru, Ishibashi Hiromi   +11 more
doaj   +1 more source

Global Validation of MODIS C6 and C6.1 Merged Aerosol Products over Diverse Vegetated Surfaces

Remote Sensing, 2018
In this study, the MODerate resolution Imaging Spectroradiometer (MODIS) Collections 6 and 6.1 merged Dark Target (DT) and Deep Blue (DB) aerosol products (DTBC6 and DTBC6.1) at 0.55 µm were validated from 2004–2014 against Aerosol Robotic Network ...
Muhammad Bilal, Majid Nazeer, Zhongfeng Qiu, Xiaoli Ding, Jing Wei   +4 more
doaj   +1 more source

Cryolipolysis on More than One Body Area Increases Lipid Peroxidation without Changing Lipid Profile and Inflammatory Markers

Biology, 2022
In the present study, the effects of cryolipolysis on one and multiple body areas, assessing body composition, lipid profile and peroxidation and inflammatory markers were investigated.
Antônio Daniel Saraiva da Costa, Amanda Suellenn da Silva Santos Oliveira, Ana Karolinne da Silva Brito, Lays Arnaud Rosal Lopes, Maísa Guimarães Silva Primo, Ana Lina de Carvalho Cunha Sales, Marcos Antônio Pereira dos Santos, Nara Vanessa dos Anjos Barros, Oséas Florêncio de Moura-Filho, Jaynara Keylla Moreira da Silva, Edwiges Ita de Miranda Moura, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Maria do Carmo de Carvalho e Martins   +14 more
doaj   +1 more source

Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? [PDF]

, 2003
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially ...
Alan J. Jaap, Andersen, Anderson, Ann Rumley, Anne Kelly, Brussard, Cushman, Dichtl, Ferrara, Gordon D. Lowe, Gornstein, Herrington, Hokanson, Hulley, Ian A. Greer, John R. Petrie, Joyce McKenzie, Kanaya, Kenneth Paterson, Knopp, Koh, Kroon, Kroon, Lokkegaard, Lowe, Lowe, Lowe, Lynne Crawford, Manning, Meade, Naveed Sattar, Perera, Petitti, Pradhan, Rapp, Ridker, Ridker, Rossouw, Sattar, Sattar, Stephen Gallacher, Stork, Van Baal, Van Baal, Vehkavaara, Woodward, Zanger   +46 more
core   +1 more source

Coherent Control of Defect Spins in Silicon Carbide above 550 K [PDF]

Physical Review Applied, 2018
Great efforts have been made to the investigation of defects in silicon carbide for their attractive optical and spin properties. However, most of the researches are implemented at low and room temperature.
Fei-Fei Yan, Jun-Feng Wang, Qiang Li, Ze-Di Cheng, Jinming Cui, Wen-Zheng Liu, Jin-Shi Xu, Chuan‐Feng Li, G. Guo   +8 more
semanticscholar   +1 more source

Complicações em 550 cirurgias consecutivas de implante coclear Surgical complications in 550 consecutive cochlear implantation

Brazilian Journal of Otorhinolaryngology, 2012
A cirurgia de implante coclear (IC) é método seguro e factível de restaurar audição em pacientes com surdez grave a profunda. OBJETIVO: Descrever complicações do IC.
Rubens Brito, Tatiana Alves Monteiro, Aquiles Figueiredo Leal, Robinson Koji Tsuji, Mariana Hausen Pinna, Ricardo Ferreira Bento   +5 more
doaj   +1 more source

Spreading of Kaolin and Sand Mixtures on a Horizontal Plane: Physical Experiments and SPH Numerical Modelling [PDF]

, 2017
open4noThe investigation of the collapse of a well-known soil volume is a simple experiment that permits to make several interesting considerations. This paper, at first, presents a brief overview of some physical experiments led to understand how the ...
Brezzi, Lorenzo, Cola, Simonetta, Gabrieli, Fabio, Gidoni, Giacomo   +3 more
core   +1 more source

Effect of intake of virgin coconut oil (Cocos nucifera L.) on the spleen and small intestinal immune cells and liver lipid of mice

Ceylon Journal of Science, 2021
Virgin coconut oil (Cocos nucifera L.) (VCO) is consumed worldwide and is rich in medium-chain fatty acids (MCFAs) and lauric acid (LA). The aim of this study was to examine the immuno-stimulation effect of VCO produced in Sri Lanka. Three groups of mice
N. Komatsuzaki, S. Arai, S. Fujihara, R. G. S. Wijesekara   +3 more
doaj   +1 more source