Results 71 to 80 of about 1,303,684 (338)
The Education (Pupil Registration) (England) (Amendment) Regulations 2013 [PDF]
Enabling power: Education Act 1996, ss. 434 (3), 551 (1), 569 (4). Issued: 04.04.2013. Made: 26.03.2013. Laid: 04.04.2013. Coming into force: 01.09.2013. Effect: S.I. 2006/1751 amended.
core
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang+16 more
wiley +1 more source
Fifteen new dinuclear arene‐ruthenium (II)‐BODIPY conjugates were synthesized. Despite a fluorescence quenching effect, these conjugates can be used as fluorescent tracers. Their antiparasitic activity but also their toxicity against healthy human foreskin fibroblasts (HFFs) was reduced compared to the parent ruthenium compounds.
Oksana Desiatkina+6 more
wiley +1 more source
The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men [PDF]
Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out
Lennon, L.+6 more
core +1 more source
They developed a bimodal EV‐circRNA in situ analyzer (BEISA) using a DNA rectangular frame‐guided hybridization chain reaction (RF‐HCR) system. By combining ML algorithms and bimodal EV‐circRNA in situ analysis, this platform provides a promising tool for the analysis of gastric cancer‐derived EV‐circRNA, making diagnosis and staging of gastric cancer ...
Yuhang Guo+11 more
wiley +1 more source
Abstract Background In patients with some cardiovascular disease conditions, slightly elevated body mass index (BMI) is associated with a lower mortality risk (termed “obesity paradox”). It is uncertain, however, if this obesity paradox exists in patients who have had invasive cardiology procedures.
Jari A. Laukkanen+16 more
wiley +1 more source
This study used bibliometric analysis to investigate the research on Attention-Deficit/Hyperactivity Disorder (ADHD) in pediatric populations between January 2014 and January 2024.
Mohamed E. Elnageeb+9 more
doaj +1 more source
An Efficient Top-k Query Scheme Based on Multilayer Grouping
The top-k query is to find the k data that has the highest scores from a candidate dataset. Sorting is a common method to find out top-k results. However, most of existing methods are not efficient enough.
Zongmin Cui+5 more
doaj +1 more source
β-blocker eye drops affect ocular surface through β2 adrenoceptor of corneal limbal stem cells
Background Topical application of β-blocker eye drops induces damage to the ocular surface in clinical. However, the mechanism involved remains incompletely understood. The purpose of this study was to investigate the influence and mechanism of β-blocker
Xingyue Yuan+4 more
doaj +1 more source
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao+11 more
wiley +1 more source