Results 71 to 80 of about 1,303,684 (338)

The Education (Pupil Registration) (England) (Amendment) Regulations 2013 [PDF]

open access: yes, 2013
Enabling power: Education Act 1996, ss. 434 (3), 551 (1), 569 (4). Issued: 04.04.2013. Made: 26.03.2013. Laid: 04.04.2013. Coming into force: 01.09.2013. Effect: S.I. 2006/1751 amended.

core  

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

open access: yesAdvanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang   +16 more
wiley   +1 more source

Synthesis, Photophysical Properties and Biological Evaluation of New Conjugates BODIPY: Dinuclear Trithiolato‐Bridged Ruthenium(II)‐Arene Complexes

open access: yesChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
Fifteen new dinuclear arene‐ruthenium (II)‐BODIPY conjugates were synthesized. Despite a fluorescence quenching effect, these conjugates can be used as fluorescent tracers. Their antiparasitic activity but also their toxicity against healthy human foreskin fibroblasts (HFFs) was reduced compared to the parent ruthenium compounds.
Oksana Desiatkina   +6 more
wiley   +1 more source

The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men [PDF]

open access: yes, 2003
Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out
Lennon, L.   +6 more
core   +1 more source

Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection

open access: yesAdvanced Science, EarlyView.
They developed a bimodal EV‐circRNA in situ analyzer (BEISA) using a DNA rectangular frame‐guided hybridization chain reaction (RF‐HCR) system. By combining ML algorithms and bimodal EV‐circRNA in situ analysis, this platform provides a promising tool for the analysis of gastric cancer‐derived EV‐circRNA, making diagnosis and staging of gastric cancer ...
Yuhang Guo   +11 more
wiley   +1 more source

Underweight and obesity are related to higher mortality in patients undergoing coronary angiography: The KARDIO invasive cardiology register study

open access: yesCatheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1242-1251, December 1, 2022., 2022
Abstract Background In patients with some cardiovascular disease conditions, slightly elevated body mass index (BMI) is associated with a lower mortality risk (termed “obesity paradox”). It is uncertain, however, if this obesity paradox exists in patients who have had invasive cardiology procedures.
Jari A. Laukkanen   +16 more
wiley   +1 more source

Interdisciplinary Insights and Global Perspectives on ADHD in Children: A Comprehensive Bibliometric Analysis (2014–2024)

open access: yesPsychiatry International
This study used bibliometric analysis to investigate the research on Attention-Deficit/Hyperactivity Disorder (ADHD) in pediatric populations between January 2014 and January 2024.
Mohamed E. Elnageeb   +9 more
doaj   +1 more source

An Efficient Top-k Query Scheme Based on Multilayer Grouping

open access: yesTehnički Vjesnik, 2019
The top-k query is to find the k data that has the highest scores from a candidate dataset. Sorting is a common method to find out top-k results. However, most of existing methods are not efficient enough.
Zongmin Cui   +5 more
doaj   +1 more source

β-blocker eye drops affect ocular surface through β2 adrenoceptor of corneal limbal stem cells

open access: yesBMC Ophthalmology, 2021
Background Topical application of β-blocker eye drops induces damage to the ocular surface in clinical. However, the mechanism involved remains incompletely understood. The purpose of this study was to investigate the influence and mechanism of β-blocker
Xingyue Yuan   +4 more
doaj   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao   +11 more
wiley   +1 more source

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