Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey [PDF]
This study aimed to evaluate KRAS and NRAS mutations over an eight‐year period to provide a comprehensive understanding of the genetic landscape of metastatic colorectal cancer (mCRC) in Turkish patients.
Gozde Kavgaci +6 more
doaj +3 more sources
#5699 IS GFR DECLINE INDUCED BY SGLT-2 INHIBITOR OF CLINICAL IMPORTANCE?
Abstract Background and Aims Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are associated with better cardiovascular outcome and with nephroprotection independent of diabetes status. However, the use of SGLT2i often cause an initial decline in estimated glomerular filtration rate (eGFR).
Agnes Bosch +2 more
exaly +2 more sources
Four Centuries of Clinical Chemistry. Louis Rosenfeld. Amsterdam, The Netherlands: Gordon and Breach Science Publishers, 1999, 592 pp., $149.00. ISBN 90-5699-645-2. [PDF]
This 500-plus page book represents an enormous effort and describes in great detail the development of many areas of clinical chemistry. The author has a passion for his subject and a great understanding of the principles of chemistry and their application to clinical issues.
Amadeo J Pesce
exaly +2 more sources
Transcriptome-wide association study identifies genes associated with bladder cancer risk [PDF]
Genome-wide association studies (GWAS) have detected several susceptibility variants for urinary bladder cancer, but how gene regulation affects disease development remains unclear.
Siting Li +3 more
doaj +2 more sources
Influence of atmospheric deposition on biogeochemical cycles in an oligotrophic ocean system [PDF]
The surface mixed layer (ML) in the Mediterranean Sea is a well-stratified domain characterized by low macronutrients and low chlorophyll content for almost 6 months of the year. In this study we characterize the biogeochemical cycling of nitrogen (N) in
F. Van Wambeke +9 more
doaj +1 more source
Measurement Report: Wintertime new particle formation in the rural area of the North China Plain – influencing factors and possible formation mechanism [PDF]
The high concentration of fine particles and gaseous pollutants makes polluted areas, such as the urban setting of North China Plain (NCP) of China, a different environment for new particle formation (NPF) compared to many clean regions.
J. Hong +33 more
doaj +1 more source
Epiphyte type and sampling height impact mesofauna communities in Douglas-fir trees [PDF]
Branches and boles of trees in wet forests are often carpeted with lichens and bryophytes capable of providing periodically saturated habitat suitable for microfauna, animals that include tardigrades, rotifers, nematodes, mites, and springtails. Although
Alexander R. Young +4 more
doaj +2 more sources
mSphere of Influence: Interferon Ultra Is a Means To Fight Viral Disease
Connor G. G. Bamford works in the fields of virology and innate immunity. In this mSphere of Influence article, he reflects on how three papers by Manry et al. (J. Manry, G. Laval, E. Patin, S.
Connor G. G. Bamford
doaj +1 more source
Comparison of published palaeoclimate records suitable for reconstructing annual to sub-decadal hydroclimatic variability in eastern Australia: implications for water resource management and planning [PDF]
Knowledge of past, current, and future hydroclimatic risk is of great importance. However, like many other countries, Australia's observed hydroclimate records are at best only ∼ 120 years long (i.e.
A. L. Flack +7 more
doaj +1 more source

