Results 151 to 160 of about 386,450 (264)
Preparation of Transparent and Scratch-Resistant Organic-Inorganic Hybrid Coatings: Role and Mechanism of Silane-Modified Nano-SiO<sub>2</sub>. [PDF]
Wang S +7 more
europepmc +1 more source
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
On-surface synthesis and interfacial charge redistribution of open-shell [3]triangulene-fused porphyrins on Au(111). [PDF]
Martínez García M +10 more
europepmc +1 more source
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan +6 more
wiley +1 more source
Mechanistic design of cell-penetrating disruptors for phospho-dependent TACC3-CHC interaction. [PDF]
Gunning V +8 more
europepmc +1 more source
Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu +7 more
wiley +1 more source
Analysis of rational use and misuse of antibiotics in emergency departments: A cross-sectional study. [PDF]
Gurbuz H, Aslan S, Doğan ME, Çevik MA.
europepmc +1 more source
This study demonstrates, for the first time, the use of a large‐format high‐pressure press to modify synthesized Li2SrSiO4:Eu2+,Cs+ phosphors after its preparation. The pressure treatment results in the formation of new materials with distinctive optical properties, opening pathways for the development of advanced LED devices and high‐performance ...
Przemysław Woźny +9 more
wiley +1 more source

