Results 211 to 220 of about 2,142,958 (287)

Stress cardiomyopathy following antibiotic-induced anaphylaxis in a 16-month-old child. [PDF]

Ann Pediatr Cardiol
Reddy MN, Keerthy R, Gudipati RB, Lotkal RR.   +3 more
europepmc   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Augmented Reality-Assisted vs Manual Total Knee Arthroplasty: Clinical and Perioperative Outcomes in a Consecutive Single-Surgeon Cohort. [PDF]

Arthroplast Today
Farner N, Jawanda G, Santiago-Rivera OJ, Kassab SS.   +3 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Convergence on a Senescence‐Associated B Cell–MIF Signaling Axis in Joint Aging and Osteoarthritis Progression

Advanced Science, EarlyView.
Single‐cell and spatial transcriptomics implicate senescent B cells and macrophage migration inhibitory factor (MIF) signaling in aging and osteoarthritic joints. An injectable hydrogel combining quercetin with siRNA targeting MIF attenuates cartilage degeneration in a mouse model of osteoarthritis.
Weida Li, Yi Wang, Yongqing You, Yue Cui, Jiayun Liu, Xingbiao Ma, QiuYu Zhu, Qiang Wu, Zanjing Zhai, Zuyan Lu, Kerong Dai, Ye Sun   +11 more
wiley   +1 more source

Lactylation of HSC70 Impairs Chaperone‐Mediated Autophagy to Promote Pyrin Inflammasome‐Dependent PANoptosis in Macrophages During Sepsis

Advanced Science, EarlyView.
In sepsis, lactate accumulation drives HSC70 K561 lactylation, which impairs chaperone‐mediated autophagy and blocks CUX1 degradation. Accumulated CUX1 transcriptionally upregulates Pyrin, triggering PANoptosis in macrophages and exacerbating inflammatory storm and organ injury.
Ying Chen, Yan Zhang, Pei Wang, Jiamin Ma, Xinru Zhao, Yi Li, Zhenghao Deng, Xueqing Meng, Jiali Zhu, Liangfang Yao, Jinbao Li   +10 more
wiley   +1 more source

l-Talitol. [PDF]

IUCrdata
Takashita T, Horii Y, Miyoshi S, Ishii T.   +3 more
europepmc   +1 more source

18F‐FGln PET/CT Imaging of Glutamine Uptake Has Potential for Predicting Immunotherapy Response in Hepatocellular Carcinoma

Advanced Science, EarlyView.
18F‐FGln PET/CT imaging serves as a marker of Gln uptake in hepatocellular carcinoma. Tumors with high Gln uptake drive Treg‐mediated immunosuppression and immune evasion during antitumor immunotherapy. Conversely, tumors with low Gln uptake maintain sufficient Gln in the TME, suppressing Tregs and enabling cytotoxic T cells to inhibit tumor growth ...
Yi Liu, Jindian Li, Xiaoyu Pan, Xiaoping Xu, Xuan Huang, Simin He, Jianping Zhang, Fei Liu, Shaoli Song   +8 more
wiley   +1 more source

Mechanically‐Gated Stochastic Resonance for All‐Optical Acoustic Sensing in Noisy Environments

Advanced Science, EarlyView.
A mechanically‐gated stochastic resonance (MGSR) sensing system is demonstrated, wherein stochastic resonance is enabled by an all‐optical bistable fiber Bragg grating feedback loop and gated by mechanical resonance. Under ambient noise, the system generates bistable outputs satisfying the Kramers escape‐rate condition, yielding signal‐to‐noise ratio ...
Xuyu Zhang, Minzheng Sun, Cunzheng Fan, Shuolong Zhu, Qilin Hong, Pan Xu, Min Zhu, Zhengliang Hu, Yongchao Zou, Qizhen Sun   +9 more
wiley   +1 more source

Deconvolution and Correction of the Inner Filter Effect in a Tri-Enzymatic Fluorescent Cascade for Ultra-Extended Cholesterol Quantification. [PDF]

Luminescence
Yadav SK.
europepmc   +1 more source