Results 61 to 70 of about 1,476,815 (405)

ISA 570: Italian Auditors’ and Academics’ Perceptions of the Going Concern Opinion

open access: yes, 2019
This study aims to identify which of the indicators used to assess whether an entity may not be able to continue as a going concern are regarded by Italian partners in auditing firms and Italian accounting and finance academics as being the most ...
F. Bava, Melchior Gromis di Trana
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

2-(2-Isopropylphenoxy)acetic acid

open access: yesIUCrData, 2016
In the title compound, C11H14O3, the pendant –OCH2COOH chain is in an extended conformation and almost lies in the plane of the benzene ring, as indicated by the dihedral angle of 2.61 (5)°.
Yasser Hussein Issa Mohammed   +5 more
doaj   +1 more source

CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients

open access: yesLeukemia, 2014
Current prognostication in primary myelofibrosis (PMF) is based on the dynamic international prognostic scoring system (DIPSS)-plus, which employs clinical and cytogenetic variables. We recently reported DIPSS-plus independent prognostic significance for
A. Tefferi   +12 more
semanticscholar   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 699-713, May 2025.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo   +2 more
wiley   +1 more source

The wave function of a gravitating shell [PDF]

open access: yesJ.Exp.Theor.Phys.111:570-775,2010, 2010
We have calculated a discrete spectrum and found an exact analytical solution in the form of Meixner polynomials for the wave function of a thin gravitating shell in the Reissner-Nordstrom geometry. We show that there is no extreme state in the quantum spectrum of the gravitating shell, as in the case of extreme black hole.
arxiv   +1 more source

Steady as She Goes: State and Local Government Revenues and Spending in Oregon [PDF]

open access: yes, 2007
State and local governments raise and spend money primarily to educate our children, keep our communities safe, arbitrate disputes through the courts, and provide health care and other services for our most vulnerable neighbors.
Michael Leachman
core  

High-power 1.3 µm superluminescent diode [PDF]

open access: yes, 1989
Superluminescent diodes with high output power (10 mW at 175 mA), wide spectral width (28 nm), low spectral modulation depth (
Bar-Chaim, Nadav   +2 more
core   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 793-809, May 2025.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

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