Results 41 to 50 of about 465,485 (233)

(4-Fluorophenyl)(4-hydroxy-3-methylphenyl)methanone

Acta Crystallographica Section E, 2014
In the title compound, C14H11FO2, the two benzene rings are not coplanar, with a dihedral angle of 57.45 (12)° between their planes. In the crystal, molecules are linked by an O—H...O hydrogen bond, forming a 21 helical chain along the b axis.
C. S. Dileep, V. Lakshmi Ranganatha, N. K. Lokanath, S. A. Khanum, M. A. Sridhar   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Screening for Folate Producing Lactic Acid Bacteria from Colostrum and Characterization of their Probiotic Potential

Journal of Pure and Applied Microbiology, 2018
Folate represents an essential nutritional component in human diet and involved in many metabolic pathways, its deficiency results in disorders like megaloblastic anemia and neural tube defects. The present study reports screening of lactic acid bacteria
H.M. Bhagya, B. Renuka, Mahadeva Naika, H. V. Batra , H.S. Murali   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

3-(1-{[1-(4-Bromophenyl)-1H-1,2,3-triazol-4-yl]methyl}piperidin-4-yl)-6-fluoro-1,2-benzoxazole hemihydrate

IUCrData, 2016
The title compound, C21H19BrFN5O·0.5H2O, crystallizes as a hemihydrate with the water molecule located on a twofold rotation axis. The piperidine ring has a chair conformation, whereas the triazole and the benzisoxazole rings are planar (r.m.s ...
N. Ashwini, S. Naveen, K. S. Rakesh, N. K. Lokanath, K. S. Rangappa   +4 more
doaj   +1 more source

ADC 570

, 2009
onderzoeksrappor
Rijk, P. de
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

XAI-Driven Malware Detection from Memory Artifacts: An Alert-Driven AI Framework with TabNet and Ensemble Classification

AI
Modern malware presents significant challenges to traditional detection methods, often leveraging fileless techniques, in-memory execution, and process injection to evade antivirus and signature-based systems.
Aristeidis Mystakidis, Grigorios Kalogiannnis, Nikolaos Vakakis, Nikolaos Altanis, Konstantina Milousi, Iason Somarakis, Gabriela Mihalachi, Mariana S. Mazi, Dimitris Sotos, Antonis Voulgaridis, Christos Tjortjis, Konstantinos Votis, Dimitrios Tzovaras   +12 more
doaj   +1 more source

(4-Fluorophenyl)(2-hydroxy-5-methylphenyl)methanone

Acta Crystallographica Section E, 2014
In the title compound, C14H11FO2, the dihedral angles beteen the central C3O ketone residue and the fluoro- and hydroxy-substituted benzene rings are 50.44 (9) and 12.63 (10)°, respectively.
C. S. Dileep, V. Lakshmi Ranganatha, N. K. Lokanath, S. A. Khanum, M. A. Sridhar   +4 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source