Results 51 to 60 of about 7,197,190 (271)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Trait openness and agreeableness are related to a left-leaning political orientation but are negatively related to the endorsement of totalitarian ideals [PDF]
, 2019 Although relationships between temperament and political orientation are well established [1-2], it is unclear whether they are moderated by opinions on how we should execute our political ambitions, with or without regard to individual liberty.
Hollick, David W. +1 more
core
Principal Components of Short-term Variability in Venus' UV Albedo
, 2019 We explore the dominant modes of variability in the observed albedo at the cloud tops of Venus using the Akatsuki UVI 283-nm and 365-nm observations, which are sensitive to SO2 and unknown UV absorber distributions respectively, over the period Dec 2016 ...
Imamura, Takeshi +3 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
EDIS, 2018 This 5-page fact sheet is part of the 2018–2019 Florida Citrus Production Guide. The insects listed in this section are generalist feeders for which citrus is not a preferred host. They are, therefore, only sporadic problems in Florida citrus.
Philip A. Stansly +2 more
doaj +5 more sources
Investigating 16O with the 15N(p,{\alpha})12C reaction
, 2018 The 16O nucleus was investigated through the 15N(p,{\alpha})12C reaction at excitation energies from Ex = 12 231 to 15 700 keV using proton beams from a 5 MeV Van de Graaff accelerator at beam energies of Ep = 331 to 3800 keV.
Andersen, K. L. +4 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
tripleC: Communication, Capitalism & Critique, 2018 This contribution is part of a debate between Michael Hardt/Toni Negri and David Harvey on the occasion of Marx’s bicentenary (May 5, 2018). The discussion focuses on the question of what capitalism looks like today and how it can best be challenged. In
David Harvey
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source