Results 71 to 80 of about 7,197,190 (271)
Exceptional Retreat of Kangerlussuaq Glacier, East Greenland, Between 2016 and 2018
Frontiers in Earth Science, 2019 Kangerlussuaq Glacier is one of Greenland’s largest tidewater outlet glaciers, accounting for approximately 5% of all ice discharge from the Greenland ice sheet.
Stephen Brough +3 more
doaj +1 more source
Di-san junyi daxue xuebao, 2020 Objective To analyze copy number variations (CNVs) of pfpm2 gene in 122 imported cases of Palciparum falciparum (P.f) infection in Changsha from 2016 to 2019 for predicting the risk of imported drug-resistant P.f strains in Changsha. Methods We collected
TIAN Bin +4 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effects of Volcanic Emissions on Clouds During Kilauea Degassing Events [PDF]
Aerosols influence Earths radiative balance directly by scattering and absorbing solar radiation, and indirectly by modifying cloud properties. Current scientific consensus indicates that these effects may offset as much as 50% of the warming due to ...
Barahona, D. +3 more
core +1 more source
Association between 5-Year clinical outcome in patients with nonmedically evacuated mild blast traumatic brain injury and clinical measures collected within 7 days postinjury in combat [PDF]
, 2019 Importance: Although previous work has examined clinical outcomes in combat-deployed veterans, questions remain regarding how symptoms evolve or resolve following mild blast traumatic brain injury (TBI) treated in theater and their association with long ...
Barber, Jason +6 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
SATISFACTION AND EXPERIENCE WITH THE UNITY SUSPENSION SYSTEM
Canadian Prosthetics & Orthotics Journal, 2018 BACKGROUND While elevated vacuum suspension systems have some benefits over the other suspension approaches 1–5, elevated vacuum may not be appropriate for all amputees.
Hossein Gholizadeh +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source