Results 31 to 40 of about 228,146 (229)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

DSEP Fulcrum: Dynamic Sparsity and Expansion Packets for Fulcrum Network Coding

IEEE Access, 2020
Fulcrum coding combines a high-field outer Random Linear Network Coding (RLNC) that generates outer coding expansion packets with a small-field inner RLNC that combines the source packets and the outer coding expansion packets.
Vu Nguyen, Elif Tasdemir, Giang T. Nguyen, Daniel E. Lucani, Frank H. P. Fitzek, Martin Reisslein   +5 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Security of Topology Discovery Service in SDN: Vulnerabilities and Countermeasures

IEEE Open Journal of the Communications Society
Software-Defined Network (SDN) controller needs comprehensive visibility of the whole network to provide effective routing and forwarding decisions in the data layer.
Sanaz Soltani, Ali Amanlou, Mohammad Shojafar, Rahim Tafazolli   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Energy Beamforming for MIMO WIPT Relaying With Arbitrary Correlation

IEEE Access, 2018
This paper investigates the negative impact of spatial fading correlation in multiple-input multiple-output relaying systems on the performance of energy beamforming.
Ahmed Almradi, Pei Xiao
doaj   +1 more source

Filtered OFDM: An Insight Into Intrinsic In-Band Interference and Filter Frequency Response Selectivity

IEEE Access, 2020
The future mobile networks will face challenges in support of heterogeneous services over a unified physical layer, calling for a waveform with good frequency localization. Filtered orthogonal frequency division multiplexing (f-OFDM), as a representative
Juquan Mao, Lei Zhang, Pei Xiao, Konstantinos Nikitopoulos   +3 more
doaj   +1 more source

5G and banking

Pressacademia, 2021
Purpose- Technological developments in mobile telecommunications have evolved immensely after the transition from analog technologies that were widely used in 1980s to digital technologies connecting to globe with wireless cellular technologies. This study intends to review telecommunication technologies starting 1970s (1G technology) through 2020s (5G
TEKER, Suat, TEKER, Dilek, ORMAN, Irmak
openaire   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Optimizing Near-Field XL-MIMO Communications: Advanced Feedback Framework for CSI

IEEE Access
With the successful deployment of fifth-generation (5G) systems, both industry and academia anticipate the evolution of 6G systems to meet future data-intensive needs.
Sourav Mukherjee, Mohammed Saquib Khan, Ashok Kumar Reddy Chavva   +2 more
doaj   +1 more source