Results 71 to 80 of about 327,593 (283)

PLAN DE MEJORA EN LA GESTIÓN OPERATIVA PARA REDUCIR COSTOS DE LA EMPRESA SHALOM EMPRESARIAL S.A.C. CHICLAYO

open access: yesTzhoecoen, 2020
La presente investigación tuvo como objetivo elaborar un plan de mejora en la gestión operativa para reducir costos de la empresa Shalom Empresarial S.A.C.
Juan José Ccahuay Cercado   +2 more
doaj   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

Tuotannon tehostaminen 5S-menetelmällä [PDF]

open access: yes, 2020
Opinnäytetyön tarkoituksena oli käynnistää 5S-menetelmä Sandvik Mining and Construction yrityksen porakonetuotannossa. Tavoitteena oli etsiä tapoja tehostaa tuotantoa 5S-menetelmällä.
Tsutsunen, Mikko
core  

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

open access: yesAdvanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi   +9 more
wiley   +1 more source

5S邁向TQM之個案研究

open access: yes, 2008
[[abstract]]5S(整理、整頓、清掃、清潔、修養)與TQM(全面品質管理)至少已發展二十多年,因其成效非凡,故至今仍普遍實施於業界。然而5S與TQM之關係,卻尚未見到有兩者關聯架構之文獻。因此,本研究嘗試建立以5S為基礎邁向TQM之架構,並經由參與豐田汽車集團中衛體系之輔導改善團隊,探討此架構對於企業體質提升與創造卓越品質的適用性。 本研究以該集團某協力廠商為例,剖析透過5S邁向TQM的改善過程,同時以定性與定量分析,探討改善成效。本研究發現 ...
張燦明
core  

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

open access: yesAdvanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel   +10 more
wiley   +1 more source

Lean Six Sigma sample analysis process in a microbiology laboratory [PDF]

open access: yesJournal of Medical Biochemistry, 2011
Faced with shrinking budgets, growing volumes, and personnel shortages, clinical laboratories are increasingly moving to automation to maximize output and efficiency. The best tool for improvement is the Lean Six Sigma concept. The concept reaps the full
Stoiljković Vojislav   +2 more
doaj  

Measurable 5S System

open access: yes, 2010
The 5S system consists of 5 series of activities designed to improve workplace organization and standardization. These five activities begin with the letter S: Sort, Set in order, Shine, Standardize and Sustain.
Emrullah Cayir
core   +1 more source

5S-menetelmän käyttöönotto [PDF]

open access: yes, 2020
Opinnäytetyön tavoitteena oli suunnitella ja ottaa käyttöön 5S-menetelmä, sekä sitä tukemaan ja sen seurantaa helpottamaan uusi applikaatio Sandvik Mining and Construction Oy:llä Tampereella.
Kotro, Matias
core  

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