Results 71 to 80 of about 9,083 (166)

Pseudolaric Acid B Combats Drug‐Resistant Candida albicans Infection via Dual‐Action Mechanisms of Direct Antifungals and Vaginal Microbiota Restoration

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
We propose a novel therapeutic approach against fungal infection: Pseudolaric acid B directly eradicates C. albicans via Erg11 inhibition and uniquely, restores vaginal microecological homeostasis by promoting probiotic lactobacilli, addressing both the pathogen and the dysbiotic environment.
Tianmeng Shao   +3 more
wiley   +1 more source

Karyotypic features including organizations of the 5S, 45S rDNA loci and telomeres of Scadoxus multiflorus (Amaryllidaceae)

open access: yesComparative Cytogenetics, 2016
Scadoxus multiflorus Martyn, 1795 is an ornamental plant with brilliantly colored flowers. Even though its chromosomes are rather large, there is no karyotype description reported so far.
Pansa Monkheang   +3 more
doaj   +3 more sources

Mechanobiology of the Nucleolus

open access: yesBiology of the Cell, Volume 118, Issue 2, February 2026.
Mechanical forces reshape nuclear structure and reorganize the nucleolus, altering its role in ribosome biogenesis. This review examines how mechanical cues impact nucleolar assembly and function. We propose that the nucleolus acts as a mechano‐responsive condensate integrating mechanical stress with cellular homeostasis.
Yuthika Shetty, Monika Elzbieta Dolega
wiley   +1 more source

Поліморфізм міжгенного спейсера генів 5S рРНК деяких видів роду Gentiana L.

open access: yesФактори експериментальної еволюції організмів, 2017
Aim. The aim was to determine the nucleotide sequence of non-transcribed spacer (NTS) of 5S rRNA genes in some Gentiana species of the Ukrainian flora and to study the organization of this region. Methods. DNA was isolated from leaf tissue.
I. O. Andreev   +3 more
doaj   +1 more source

Near‐complete genome assembly of a transformation‐efficient elite inbred line LH244 and its comparison with B73

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 2, Page 366-382, February 2026.
Analysis of a near‐complete assembly of the genome of the highly transformable maize inbred line LH244 revealed its high genetic similarity to B73 and will serve as a much‐needed resource for functional genomics and genome editing of maize. ABSTRACT The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and ...
Kaiwen Tan   +14 more
wiley   +1 more source

Detection and succession properties of forested vernal pools with eDNA metabarcoding

open access: yesEcological Solutions and Evidence, Volume 7, Issue 1, January–March 2026.
We examined the capacity of environmental DNA metabarcoding for studying biodiversity of forested vernal pools, using multiple assays to investigate different eukaryotic communities over space and time. Our results suggest that metabarcoding can serve as a complementary tool for ‘scaling up’ vernal pool biodiversity monitoring, illuminating ecological ...
Harrison B. Goldspiel   +5 more
wiley   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang   +14 more
wiley   +1 more source

HiMBar: A High‐Fidelity Metagenomic Barcoding Approach for Transkingdom Species Detection and Interaction Analysis in Aquatic Ecosystems

open access: yesMolecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Aquatic ecosystems host diverse organisms across all six life kingdoms, yet their complex interactions remain poorly understood, primarily due to limitations in transkingdom species detection methods. To address this limitation, we developed HiMBar (https://github.com/Xchenkai2019/HIFI_barcoding), a high‐fidelity (HiFi) metagenomic barcoding ...
Kai Chen   +14 more
wiley   +1 more source

Impact of interspecific hybridization of T. pratense × T. medium and backcrossing on genetic variability of progeny

open access: yesCzech Journal of Genetics and Plant Breeding, 2016
Red clover (Trifolium pratense L.) is a high-quality fodder crop which has been hybridized successfully with its wild relative zigzag clover (T. medium L.).
Jana DLUHOŠOVÁ   +3 more
doaj   +1 more source

Molecular cytogenetic characterization and comparison of the two cultivated Canavalia species (Fabaceae)

open access: yesComparative Cytogenetics, 2017
The two cultivated Canavalia (Adanson, 1763) species, Canavalia gladiata (N. J. von Jacquin, 1788) A. P. de Candolle, 1825 and Canavalia ensiformis (Linnaeus, 1753) A. P.
Chao-Wen She, Lin Wei, Xiang-Hui Jiang
doaj   +3 more sources

Home - About - Disclaimer - Privacy