Results 91 to 100 of about 86,120 (307)
Over 25 years ago, Pace and coworkers described an activity called RNase M5 in Bacillus subtilis cell extracts responsible for 5S ribosomal RNA maturation (Sogin & Pace, Nature, 1974, 252:598-600).
C. Condon+4 more
semanticscholar +1 more source
Isolation of high quality RNA from soil-grown Ilex paraguariensis roots suitable for next-generation sequencing and gene expression analyses [PDF]
Extraction of high quality RNA is a prerequisite for downstream application in functional genomics analyses. However, the extraction and purification of pure nucleic acids from root tissues is generally difficult due to the high concentration of ...
Acevedo, Raúl Maximiliano+4 more
core +1 more source
In situ quantification of ribosome number by electron tomography
Abstract Ribosomes, discovered in 1955 by George Palade, were initially described as small cytoplasmic particles preferentially associated with the endoplasmic reticulum (ER). Over the years, extensive research has focused on both the structure and function of ribosomes.
Mounir El Hankouri+4 more
wiley +1 more source
NSCLC lacks robust noninvasive biomarkers. We curated 2050 invasive and noninvasive samples, integrating public and in‐house plasma/exosome data. A machine learning model using five tumour‐specific piRNA signatures formed the piRNA‐Based Tumour Probability Index (pi‐TPI), achieving AUC values up to .96, demonstrating strong potential for NSCLC ...
Zitong Gao+17 more
wiley +1 more source
First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers.
doaj +1 more source
Ribosomal DNA localization on Lathyrus species chromosomes by FISH
Background Fluorescence In Situ Hybridization (FISH) played an essential role to locate the ribosomal RNA genes on the chromosomes that offered a new tool to study the chromosome structure and evolution in plant. The 45S and 5S rRNA genes are independent
Hoda B. M. Ali, Samira A. Osman
doaj +1 more source
Mirror-Image 5S Ribonucleoprotein Complexes [PDF]
After realizing mirror-image genetic replication, transcription, and reverse transcription, the biggest challenge in establishing a mirror-image version of the central dogma is to build a mirror-image ribosome-based translation machine.
Chen, Ji+6 more
core +1 more source
Pseudomonas loganensis sp. nov., is a novel strain identified through genomic and biochemical analysis, exhibits salt and pH tolerance, and harbors biosynthetic gene clusters for turnerbactin, carotenoids, and trehalose, highlighting its potential in agriculture and industrial biotechnology.
Melisa Z. Karaman+3 more
wiley +1 more source
Background Pikes represent an important genus (Esox) harbouring a pre-duplication karyotype (2n = 2x = 50) of economically important salmonid pseudopolyploids.
Radka Symonová+6 more
doaj +1 more source
Non‐coding RNAs in plant stress responses: molecular insights and agricultural applications
Summary Non‐coding RNAs (ncRNAs) have emerged as crucial regulators in plant responses to environmental stress, orchestrating complex networks that finetune gene expression under both abiotic and biotic challenges. To elucidate this intricate ncRNA crosstalk, this review comprehensively summarizes recent advances in understanding the mechanisms of key ...
Xiaotong Chen+3 more
wiley +1 more source