Results 51 to 60 of about 17,790 (205)
Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria. [PDF]
PLoS Genetics, 2014 During transcription, the nascent RNA can invade the DNA template, forming extended RNA-DNA duplexes (R-loops). Here we employ ChIP-seq in strains expressing or lacking RNase H to map targets of RNase H activity throughout the budding yeast genome.
Aziz El Hage +3 more
doaj +1 more source
Environmental Microbiology, Volume 27, Issue 4, April 2025.Thraustochytrids exhibit four distinct polyunsaturated fatty acid (PUFA) biosynthetic types: Type I (ELO/DES pathway), Type II (dual‐pathway) and Types III–IV (PUFA‐S pathway with varying gene losses). This genetic diversity in PUFA biosynthesis pathways provides new perspectives for understanding their evolutionary relationships and potential ...
Sou‐Yu Cheng +4 more
wiley +1 more source
Evolutionary dynamics of rRNA gene clusters in cichlid fish
BMC Evolutionary Biology, 2012 Background Among multigene families, ribosomal RNA (rRNA) genes are the most frequently studied and have been explored as cytogenetic markers to study the evolutionary history of karyotypes among animals and plants. In this report, we applied cytogenetic
Nakajima Rafael T +4 more
doaj +1 more source
Deciphering recent transposition patterns in plants through comparison of 811 genome assemblies
Plant Biotechnology Journal, Volume 23, Issue 4, Page 1121-1132, April 2025.Summary Transposable elements (TEs) are significant drivers of genome evolution, yet their recent dynamics and impacts within and among species, as well as the roles of host genes and non‐coding RNAs in the transposition process, remain elusive. With advancements in large‐scale pan‐genome sequencing and the development of open data sharing, large‐scale
Yan Huang, Sunil Kumar Sahu, Xin Liu
wiley +1 more source
Slip of grip of a molecular motor on a crowded track: Modeling shift of reading frame of ribosome on RNA template [PDF]
EPL, vol.114, 68005 (2016), 2016 We develop a stochastic model for the programmed frameshift of ribosomes synthesizing a protein while moving along a mRNA template. Normally the reading frame of a ribosome decodes successive triplets of nucleotides on the mRNA in a step-by-step manner.
arxiv +1 more source
Contrasting distributions and expression characteristics of transcribing repeats in Setaria viridis
The Plant Genome, Volume 18, Issue 1, March 2025.Abstract Repetitive DNA contributes significantly to plant genome size, adaptation, and evolution. However, little is understood about the transcription of repeats. This is addressed here in the plant green foxtail millet (Setaria viridis). First, we used RepeatExplorer2 to calculate the genome proportion (GP) of all repeat types and compared the GP of
Ana Luiza Franco +5 more
wiley +1 more source
Site‐Selective Modification and Labeling of Native RNA
Chemistry – A European Journal, Volume 31, Issue 12, February 25, 2025.The review highlights recent advancements in site‐selective modification and labeling of native RNA, an important area for the development of RNA therapeutics and fundamental RNA research. The applications, current challenges of existing methods and potential future direction of this field are also discussed.
Tuan‐Khoa Kha, Yiran Zhao, Ru‐Yi Zhu
wiley +1 more source
Molecular interactions between the constituents of small ribosomal subunit [PDF]
arXiv, 2012 Availability of high-resolution crystal structures of ribosomal subunits of different species opens a route to investigate about molecular interactions between its constituents and stabilization strategy. Structural analysis of the small ribosomal subunit shows that primary binder proteins are mainly employed in stabilizing the folded ribosomal RNA by ...
arxiv
Physical modeling of ribosomes along messenger RNA: estimating kinetic parameters from ribosome profiling experiments using a ballistic model [PDF]
arXiv, 2022 Gene expression consists in the synthesis of proteins from the information encoded on DNA. One of the two main steps of gene expression is the translation of messenger RNA (mRNA) into polypeptide sequences of amino acids. Here, by taking into account mRNA degradation, we model the motion of ribosomes along mRNA with a ballistic model where particles ...
arxiv
Biology Open, 2018 First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers.
doaj +1 more source