Results 61 to 70 of about 17,790 (205)

Ribosomal DNA localization on Lathyrus species chromosomes by FISH

open access: yesJournal of Genetic Engineering and Biotechnology, 2020
Background Fluorescence In Situ Hybridization (FISH) played an essential role to locate the ribosomal RNA genes on the chromosomes that offered a new tool to study the chromosome structure and evolution in plant. The 45S and 5S rRNA genes are independent
Hoda B. M. Ali, Samira A. Osman
doaj   +1 more source

Leveraging Transcriptional Signatures of Diverse Stressors for Bumble Bee Conservation

open access: yesMolecular Ecology, Volume 34, Issue 3, February 2025.
ABSTRACT Organisms in nature are subjected to a variety of stressors, often simultaneously. Foremost among stressors of key pollinators are pathogens, poor nutrition and climate change. Landscape transcriptomics can be used to decipher the relative role of stressors, provided there are unique signatures of stress that can be reliably detected in field ...
Gabriela M. Quinlan   +2 more
wiley   +1 more source

Fluctuations in protein synthesis from a single RNA template: stochastic kinetics of ribosomes [PDF]

open access: yes, 2008
Proteins are polymerized by cyclic machines called ribosome which use their messenger RNA (mRNA) track also as the corresponding template and the process is called translation. We explore, in depth and detail, the stochastic nature of the translation.
arxiv   +1 more source

Higher-order organisation of extremely amplified, potentially functional and massively methylated 5S rDNA in European pikes (Esox sp.)

open access: yesBMC Genomics, 2017
Background Pikes represent an important genus (Esox) harbouring a pre-duplication karyotype (2n = 2x = 50) of economically important salmonid pseudopolyploids.
Radka Symonová   +6 more
doaj   +1 more source

Keep calm and reboot – how cells restart transcription after DNA damage and DNA repair

open access: yesFEBS Letters, Volume 599, Issue 2, Page 275-294, January 2025.
DNA damage not only inhibits transcription but also disrupts nucleolar architecture. Upon DNA repair, it is crucial to restore RNA polymerase 1 and 2 transcription as well as nucleolar structure for cell survival. However, the mechanisms for reinstating them are complex and involve various proteins and processes that are still not fully understood ...
Lise‐Marie Donnio   +1 more
wiley   +1 more source

Ribosome self-assembly leads to overlapping reproduction cycles and increases growth rate [PDF]

open access: yesarXiv, 2018
In permissive environments, E. coli can double its dry mass every 21 minutes. During this time, ribosomes, RNA polymerases, and the proteome are all doubled. Yet, the question of how to relate bacterial doubling time to other biologically relevant time scales in the growth process remains illusive, due to the complex temporal nesting pattern of these ...
arxiv  

Metformin Exhibits Anti‐Inflammatory Effects by Regulating microRNA‐451/CXCL16 and B Cell Leukemia/Lymphoma 2 in Patients With Osteoarthritis

open access: yesACR Open Rheumatology, Volume 7, Issue 1, January 2025.
Objective Osteoarthritis (OA) is the most common cause of chronic disability in joints among older individuals. The primary goal of OA treatment is pain relief to improve the quality of life. Inflammation and aging are involved in the pathogenesis of pain in OA. In this study, we evaluated the ability of metformin to regulate microRNAs, such as miR‐451
Nahid Alimoradi   +3 more
wiley   +1 more source

The Lipid-RNA World [PDF]

open access: yesarXiv, 2012
The simplest possible beginning of abiogenesis has been a riddle from the last century, which is most successfully solved by the Lipid World hypothesis. However, origin of the next stages of evolution starting form lipids is still in dark. We propose a 'Lipid-RNA World Scenario' based on the assumption that modern stable lipid-RNA interactions are ...
arxiv  

Resurrection of an ancestral 5S rRNA

open access: yesBMC Evolutionary Biology, 2011
Background In addition to providing phylogenetic relationships, tree making procedures such as parsimony and maximum likelihood can make specific predictions of actual historical sequences.
Fox George E, Lu Qing
doaj   +1 more source

TRE5-A retrotransposition profiling reveals putative RNA polymerase III transcription complex binding sites on the Dictyostelium extrachromosomal rDNA element. [PDF]

open access: yesPLoS ONE, 2017
The amoeba Dictyostelium discoideum has a haploid genome in which two thirds of the DNA encodes proteins. Consequently, the space available for selfish mobile elements to expand without excess damage to the host genome is limited.
Thomas Spaller   +3 more
doaj   +1 more source

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