CoFold: thermodynamic RNA structure prediction with a kinetic twist [PDF]
arXiv, 2012 Existing state-of-the-art methods that take a single RNA sequence and predict the corresponding RNA secondary-structure are thermodynamic methods. These predict the most stable RNA structure, but do not consider the process of structure formation. We have by now ample experimental and theoretical evidence, however, that sequences in vivo fold while ...
arxiv
Pterostilbene Targets Hallmarks of Aging in the Gene Expression Landscape in Blood of Healthy Rats
Molecular Nutrition &Food Research, Volume 68, Issue 24, December 2024.The study characterizes transcriptomic patterns in blood of healthy rats consuming diets supplemented with polyphenols. Supplementation with pterostilbene (PTS), a dietary bioactive compound from a group of phytoestrogens, resulted in gene expression changes that are functionally linked to hallmarks of aging.
Marco A. Tello‐Palencia +14 more
wiley +1 more source
Correcting a SHAPE-directed RNA structure by a mutate-map-rescue approach [PDF]
, 2014 The three-dimensional conformations of non-coding RNAs underpin their biochemical functions but have largely eluded experimental characterization. Here, we report that integrating a classic mutation/rescue strategy with high-throughput chemical mapping enables rapid RNA structure inference with unusually strong validation. We revisit a paradigmatic 16S
arxiv +1 more source
Chromomycin A3 banding and chromosomal mapping of 45S and 5S ribosomal RNA genes in bottle gourd
Caryologia, 2021 Ribosomal DNAs and various banding patterns are landmarks in molecular cytogenetics providing useful information for karyotyping and addressing individual chromosomes.
Ahmet L. Tek +3 more
doaj
Patterns and regulation of ribosomal RNA transcription in
BMC Microbiology, 2011 Background Borrelia burgdorferi contains one 16S and two tandem sets of 23S-5S ribosomal (r) RNA genes whose patterns of transcription and regulation are unknown but are likely to be critical for survival and persistence in its hosts. Results RT-PCR of B.
Schwartz Ira +3 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2019 Background Ribosomal RNA (rRNA) consists of four non‐coding RNAs, the 28S, 5.8S, 18S, and 5S rRNA. Abnormal expression of rRNA has been found in multiple tumors, and the methylation of rDNA promoter may affect rRNA expression as an epigenetic regulatory ...
Shanshan Ha +4 more
doaj +1 more source
Conservation and loss of ribosomal RNA gene sites in diploid and polyploid
BMC Plant Biology, 2011 Background The genus Fragaria comprises species at ploidy levels ranging from diploid (2n = 2x = 14) to decaploid (2n = 10x = 70). Fluorescence in situ hybridization with 5S and 25S rDNA probes was performed to gather cytogenetic information that ...
Liu Bo, Davis Thomas M
doaj +1 more source
The sequence of 5S ribosomal RNA from two mouse cell lines [PDF]
, 1969 R. Williamson, G.G. Brownlee
openalex +1 more source
Large-scale polymorphism of heterochromatic repeats in the DNA of
BMC Plant Biology, 2007 Background The composition of the individual eukaryote's genome and its variation within a species remain poorly defined. Even for a sequenced genome such as that of the model plant Arabidopsis thaliana accession Col-0, the large arrays of ...
Comai Luca, Tyagi Anand, Davison Jerry
doaj +1 more source
REGULATION OF RIBOSOMAL RNA AND 5s RNA SYNTHESIS IN DROSOPHILA MELANOGASTER: I. BOBBED MUTANTS [PDF]
, 1972 Roberto Weinmann
openalex +1 more source