, 2018 Positive allosteric modulators (PAMs) that target the M1 muscarinic acetylcholine (ACh) receptor (M1 mAChR) are potential treatments for cognitive deficits in conditions such as Alzheimer disease and schizophrenia.
Shailesh N. Mistry (694049) +10 more
core +6 more sources
6-Hydroxy-2-methylbenzofuran-4-carboxylic Acid [PDF]
, 2020 6-Hydroxy-2-methylbenzofuran-4-carboxylic acid was synthesized in two steps, starting from 3,5-dihydroxybenzoate. The product was obtained through a direct thermal one-pot cyclization with propargyl bromide, followed by a base-catalyzed hydrolysis.
Mori M +8 more
core +2 more sources
Vibrational Stark Fields in Carboxylic Acid Dimers [PDF]
, 2022 Carboxylic acids form exceptionally stable dimers and have been used to model proton and double proton transfer processes. The stabilization energies of the carboxylic acid dimers are very weakly dependent on the nature of the substitution.
G Naresh, Patwari, Manjusha, Boda
core +2 more sources
SHORT-CHAIN CARBOXYLIC-ACIDS, A NEW CLASS OF TERATOGENS - STUDIES OF POTENTIAL BIOCHEMICAL-MECHANISMS [PDF]
, 1986 Certain short-chain carboxylic acids (SCCA) appear to share a common teratogenic potential, although the structural requirements for activity remain obscure.
Coakley, ME +5 more
core +4 more sources
The effect of aliphatic carboxylic acids on olfaction-based host-seeking of the malaria mosquito Anopheles gambiae sensu stricto [PDF]
, 2009 The role of aliphatic carboxylic acids in host-seeking response of the malaria mosquito Anopheles gambiae sensu stricto was examined both in a dual-choice olfactometer and with indoor traps.
Yu Tong Qiu +10 more
core +1 more source
Study on differential expression of 1-aminocyclopropane-1-carboxylic acid oxidase genes in table grape cv. Thompson Seedless [PDF]
, 2013 As a consequence of the non-climacteric status of grapes (Vitis vinifera), ethylene biosynthesis and signal transduction have scarcely been studied in this fruit.
González-Agüero, Mauricio +5 more
core +1 more source
Spectroscopic investigations, DFT calculations, molecular docking and MD simulations of 3-[(4-Carboxyphenyl) carbamoyl]-4-hydroxy-2-oxo-1, 2-dihydroxy quinoline-6-carboxylic acid. [PDF]
, 2022 By FT-IR, FT-Raman and DFT computations spectral characterization of 3-[(4-Carboxyphenyl) carbamoyl]-4-hydroxy-2-oxo-1, 2-dihydroxy quinoline-6-carboxylic acid was performed.
B. , Sureshkumar +7 more
core +1 more source
α-phenylisocinchomeronic and 4-azafluorenone 3-carboxylic acids
, 2020 3,6-Dimethyl-6-phenylpyridine, obtained on phenylation of 2,5-lutidine, has been used in the synthesis of α-phenylisocinchomeronic acid, derivatives of it, and also for the preparation of 4-azafluorenone 3-carboxylic acid.
Sergeeva N.D. +3 more
core +2 more sources
Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera +2 more
wiley +2 more sources
Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo [PDF]
, 2013 N-methyl-d-aspartate receptor (NMDAR) activation can initiate changes in synaptic strength, evident as long-term potentiation (LTP), and is a key molecular correlate of memory formation.
Kerry L. Spear +15 more
core +1 more source