Results 71 to 80 of about 943,126 (230)

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Diagnostic Challenges and Innovations in Thoracic Endometriosis (TE)

Quality in Sport
Endometriosis is a condition characterized by the presence of endometrial tissue in ectopic locations outside the gynecological organs. Thoracic endometriosis (TE) is a rare and underdiagnosed condition characterized by the presence of endometrial-like ...
Julia Bałoniak, Zofia Szymańska, Agnieszka Leszyńska, Zuzanna Bałoniak, Aleksandra Jonkisz, Gabriela Skurzyńska, Aleksandra Stremel, Michalina Doligalska   +7 more
doaj   +1 more source

Pathogenicity and peramivir efficacy in immunocompromised murine models of influenza B virus infection

Scientific Reports, 2017
Influenza B viruses are important human pathogens that remain inadequately studied, largely because available animal models are poorly defined. Here, we developed an immunocompromised murine models for influenza B virus infection, which we subsequently ...
Philippe Noriel Q. Pascua, Heba H. Mostafa, Bindumadhav M. Marathe, Peter Vogel, Charles J. Russell, Richard J. Webby, Elena A. Govorkova   +6 more
doaj   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

Produtividade e exportação de nutrientes em beterraba cultivada com cobertura morta e adubação orgânica Yield and nutrient export of sugar beet under mulching and organic fertilization

Revista Brasileira de Engenharia Agrícola e Ambiental, 2011
Objetivou-se, com este trabalho, avaliar o efeito da cobertura do solo e doses de lodo de lagoa de decantação de água residuária de suinocultura na produtividade e na exportação de nutrientes pela beterraba, cultivar Early Wonder.
Maria A. N. Sediyama, Marlei R. Santos, Sanzio M. Vidigal, Luís T. Salgado   +3 more
doaj   +1 more source

M\"obius invariant integrable lattice equations associated with KP and 2DTL hierarchies

, 1998
Integrable lattice equations arising in the context of singular manifold equations for scalar, multicomponent KP hierarchies and 2D Toda lattice hierarchy are considered. These equation generate the corresponding continuous hierarchy of singular manifold
Bogdanov, L. V., Konopelchenko, B. G.
core   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Solving Equations Systems Using the Penguins Search Optimization

Annals of the West University of Timisoara: Mathematics and Computer Science
The Penguin Search Optimization (PeSOA) is an optimization method based on collaborative hunting strategy of penguins. In this work, a solving linear equation systems method based on PeSOA is proposed.
Mafteiu-Scai Liviu Octavian, Mursa Andrei, Mafteiu-Scai Roxana-Teodora   +2 more
doaj   +1 more source

Relationship between the Temperature-humidity Index of Twenty-four Solar Terms and Depression [PDF]

Zhongguo quanke yixue
Background The number of depression patients has exceeded 300 million worldwide, and its high disability rate has attracted global attention. However, the relationship between temperature-humidity index (Humidex) and depression remains to be explored ...
ZHANG Wenjing, GE Xufeng, OU Xiwen, CAI Yuyang, YANG Ling, LIU Fang
doaj   +1 more source