Results 21 to 30 of about 1,613,975 (290)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2006 The GEO 600 gravitational wave detector located near Hannover in Germany is part of an international network of gravitational wave observatories.
Hild, S.
core +5 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
600 botol pensanitasi tangan untuk barisan hadapan UMP [PDF]
, 2020 KUANTAN - Universiti Malaysia Pahang (UMP) menyumbang sebanyak 600 botol pensanitasi tangan yang dihasilkan kepada petugas barisan hadapan bagi menangani penularan wabak koronavirus (Covid-19)
Nik Amirulmu'min, Nik Min
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2021 Interview with Michael Silverstone, cofounder of the company 600 Highwaymen with Abigail Browde. The interview was conducted by emails from May, 7th to August, 17th.
Emeline Jouve
doaj +1 more source
UMP sumbang 600 cecair pensanitasi tangan (hand sanitizer) buat frontliner [PDF]
, 2020 Kuantan, 6 April- Sebagai usaha membantu petugas barisan hadapan menangani penularan wabak Covid-19 ketika ini, Universiti Malaysia Pahang (UMP) menyumbang sebanyak 600 cecair pensanitasi tangan (hand-sanitizer) kepada barisan hadapan (frontliner ...
UMP, PNC
core