Results 11 to 20 of about 1,289,751 (286)

CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

Molecular Medicine, 2019
Background Cervical cancer is the third most common gynecological malignancy. Conventional treatment options are known to be ineffective for the majority of patients with advanced or recurrent cervical cancer.
Sungha Lee, Jung Yoon Ho, Jing Jing Liu, Hyewon Lee, Jae Young Park, Minwha Baik, Minji Ko, Seon Ui Lee, Youn Jin Choi, Soo Young Hur   +9 more
doaj   +1 more source

Effect of Punctal Occlusion on Blinks in Eyes with Severe Aqueous Deficient Dry Eye

Diagnostics, 2023
Punctal occlusion (PO) is considered to improve both tear-film instability and increased friction during blinking and may consequently affect blinks. The purpose of this study was to investigate the effect of PO on blinks.
Hiroaki Kato, Norihiko Yokoi, Akihide Watanabe, Aoi Komuro, Yukiko Sonomura, Chie Sotozono, Shigeru Kinoshita   +6 more
doaj   +1 more source

Jianpi-Huayu Formula Inhibits Development of Hepatocellular Carcinoma by Regulating Expression of miR-602, Which Targets the Gene

Integrative Cancer Therapies, 2020
The traditional Chinese medicine formula Jianpi-Huayu (JPHY) has been reported to be effective in the treatment of hepatocellular carcinoma (HCC). However, its underlying mechanism remains unclear.
Yajing Huang MD, Cheng Zhou MD, Huihong Wen MD, Yongxu Chen MD, Yingjie Xie MD, Xiaohe Lan MD, Juze Lin MD, PhD, Xuhui Huang MD, Yousheng Mo MD, PhD, Cong Yang MD, PhD, Qi Wang MD, PhD, Changjun Wang MD, PhD   +11 more
doaj   +1 more source

A rootstock provides water conservation for a grafted commercial tomato (Solanum lycopersicum L.) line in response to mild-drought conditions: a focus on vegetative growth and photosynthetic parameters.

PLoS ONE, 2014
The development of water stress resistant lines of commercial tomato by breeding or genetic engineering is possible, but will take considerable time before commercial varieties are available for production.
Erik T Nilsen, Joshua Freeman, Ruth Grene, James Tokuhisa   +3 more
doaj   +1 more source

The Initial Mass Function of the Stellar Association NGC 602 in the Small Magellanic Cloud with Hubble Space Telescope ACS Observations [PDF]

, 2008
We present our photometric study of the stellar association NGC 602 in the wing of the Small Magellanic Cloud (SMC). The data were taken in the filters F555W and F814W using the Advanced Camera for Surveys (ACS) on-board the Hubble Space Telescope (HST).
Andrew E. Dolphin, Bruck M. T., Davies R. D., Dimitrios A. Gouliermis, Hennekemper E., Koornneef J., Markus Schmalzl, Piatti A. E., Romaniello M., Siess L., Stahler S. W., Thomas Henning, Westerlund B. E., Zinnecker H.   +13 more
core   +1 more source

Pulmonary Pleomorphic Carcinoma Harboring EGFR Mutation Successfully Treated with Osimertinib: A Case Report

Medicina, 2022
Pulmonary pleomorphic carcinoma (PPC) is well-known for its aggressive nature that is usually resistant to platinum-based chemotherapy. On the other hand, the efficacy of an immune checkpoint inhibitor-based regimen in PPC has been elucidated.
Yukari Kano, Nobutaka Kataoka, Yusuke Kunimatsu, Rei Tsutsumi, Izumi Sato, Mai Tanimura, Takayuki Nakano, Keiko Tanimura, Takayuki Takeda   +8 more
doaj   +1 more source

A Comparison of Monoscopic and Stereoscopic 3D Visualizations: Effect on Spatial Planning in Digital Twins

Remote Sensing, 2021
From the user perspective, 3D geospatial data visualizations are one of the bridges between the physical and the digital world. As such, the potential of 3D geospatial data visualizations is frequently discussed within and beyond the digital twins.
Lukáš Herman, Vojtěch Juřík, Dajana Snopková, Jiří Chmelík, Pavel Ugwitz, Zdeněk Stachoň, Čeněk Šašinka, Tomáš Řezník   +7 more
doaj   +1 more source

Bevacizumab-Containing Chemoimmunotherapy for Recurrent Non-Small-Cell Lung Cancer after Chemoradiotherapy: Case Report

Medicina, 2021
Chemoimmunotherapy has become the standard of care as the first-line treatment of advanced or recurrent non-small-cell lung cancer (NSCLC). The bevacizumab-containing chemoimmunotherapy regimen is theoretically more effective than a non-bevacizumab ...
Nobutaka Kataoka, Yusuke Kunimatsu, Rei Tsutsumi, Nozomi Tani, Izumi Sato, Mai Tanimura, Takayuki Nakano, Keiko Tanimura, Daishiro Kato, Takayuki Takeda   +9 more
doaj   +1 more source

ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway

Stem Cells International, 2021
Schwann cells (SCs) are likely to be a vital component of cell-based therapies for nerve regeneration. There are various methods for inducing SC-like cells (SCLCs) from adipose-derived stem cells (ADSCs), but their phenotypic and functional ...
Seiji Sawai, Tsunao Kishida, Shin-ichiro Kotani, Shinji Tsuchida, Ryo Oda, Hiroyoshi Fujiwara, Kenji Takahashi, Osam Mazda, Yoshihiro Sowa   +8 more
doaj   +1 more source

Experimental Evidence of the Long-Term Survival of Infective African Swine Fever Virus Strain Ba71V in Soil under Different Conditions

Pathogens, 2022
The survival of African swine fever virus (ASFV) on different matrices and its infectivity in wild as well as domestic swine is still a matter of interest.
Jana Prodelalova, Lenka Kavanova, Jiri Salat, Romana Moutelikova, Sarka Kobzova, Magdalena Krasna, Petra Vasickova, Bronislav Simek, Petr Vaclavek   +8 more
doaj   +1 more source