Results 161 to 170 of about 201,207 (262)

Segmented Therapeutic Delivery via Acoustic Microbubble Relay

open access: yesAdvanced Intelligent Systems, EarlyView.
An acoustically driven, modular segmented delivery system is presented to overcome mechanical limitations of conventional microcatheters. Oscillating microbubbles generate directional streaming that enables continuous, targeted transport across open, angled segments.
Lei Wang   +6 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland   +4 more
wiley   +1 more source

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

open access: yesAngewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou   +7 more
wiley   +2 more sources

The emergence and biological characteristics of linezolid-resistant <i>Clostridioides difficile</i> isolates in the Asia-Pacific region. [PDF]

open access: yesEmerg Microbes Infect
Chen Y   +13 more
europepmc   +1 more source

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

open access: yesAnimal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala   +6 more
wiley   +1 more source

Tunable Synthesis of Multi‐Responsive NH‐Containing Helical Nanographenes With a Chiroptical Switching Function

open access: yesAngewandte Chemie, EarlyView.
The Scholl reaction of 1,3,6,8‐tetrakis(oligophenyl)‐appended carbazoles afforded stable NH‐containing helical nanographenes, which showed significant redshift and reversible on/off switching of CPL upon the addition of base and acid, respectively. Furthermore, excited‐state proton transfer occurred in dimethyl sulfoxide to generate anionic species ...
Chihiro Maeda   +7 more
wiley   +2 more sources

Adjuvant anti-PD-1 therapy in high-risk cutaneous squamous-cell carcinoma: <i>post hoc</i> insights from the C-POST and KEYNOTE-630 studies. [PDF]

open access: yesImmunooncol Technol
Cavalieri S   +7 more
europepmc   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

open access: yesAnnals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti   +17 more
wiley   +1 more source

Energy Transfer‐Mediated Magnetoluminescence of an Octahedral MnII Complex Ligated With Bis(Diphenylphosphino)Methane Dioxide

open access: yesAngewandte Chemie, EarlyView.
Energy‐transfer‐mediated magnetoluminescence of paramagnetic transition metal complexes: dope solids of an octahedral MnII complex into the corresponding ZnII complex exhibited a pronounced magnetic field response of emission spectra under the application of magnetic fields.
Asato Mizuno   +5 more
wiley   +2 more sources

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