Results 1 to 10 of about 1,313,156 (149)
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy [PDF]
IgA nephropathy (IgAN) is the most common primary glomerular disease. The characteristic pathology involves immune complexes formed by the deposition of IgA1 and underglycosylated IgA1 aggregates in the mesangial area, which may be accompanied by the ...
Chan Liu +5 more
doaj +5 more sources
Increased microRNA-630 expression in gastric cancer is associated with poor overall survival. [PDF]
MicroRNAs are noncoding RNAs that regulate multiple cellular processes during cancer progression. Among various microRNAs, MiR-630 has recently been identified to be implicated in many critical processes in human malignancies. We aimed to investigate the
Dake Chu +7 more
doaj +5 more sources
miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis [PDF]
Background MicroRNAs (miRNAs) are critical regulators of cancer progression, prompting our investigation into the specific function of miR-630 in pancreatic cancer stem cells (PCSCs).
Jun Zou +5 more
doaj +2 more sources
miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3 [PDF]
Cataract, an eye disease that threatens the health of millions of people, brings about severe economic burden for patients and society. MicroRNA (miR)-378a-5p and miR-630 were recognized as essential regulators in multiple cancers.
Weiwei Gao, Xiaoqing Zhou, Ruihua Lin
doaj +1 more source
Purpose. Hypoxia has crucial functions in the development and metastasis of cervical cancer by inducing the expression of numerous genes, including microRNA genes.
Qiaohui Gao +6 more
doaj +1 more source
Ovarian cancer (OC) is a lethal gynecological malignancy. Extracellular vesicles (EVs) are crucial media in cell-to-cell communication by carrying microRNAs (miRs).
Yulan Cui, Deying Wang, Min Xie
doaj +1 more source
MicroRNA expression profiles of whole blood in lung adenocarcinoma. [PDF]
The association of lung cancer with changes in microRNAs in plasma shown in multiple studies suggests a utility for circulating microRNA biomarkers in non-invasive detection of the disease.
Santosh K Patnaik +5 more
doaj +1 more source
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin +10 more
doaj +1 more source
Molecular genetics of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic
R. N. Mustafin
doaj +1 more source
The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik +6 more
doaj +1 more source

