Results 21 to 30 of about 3,995 (136)
microRNA Expression Profiling in Young Prostate Cancer Patients [PDF]
, 2020 MicroRNAs (miRNAs) are small, non-coding RNA molecules with multiple roles in many biological processes. Few studies have shown the molecular characteristics in younger prostate cancer (PCa) patients.
Merino, Maria J +4 more
core +1 more source
MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro [PDF]
, 2021 HER2-positive (HER2+) breast cancer patients that do not respond to targeted treatment have a poor prognosis. The effects of targeted treatment on endogenous microRNA (miRNA) expression levels are unclear.
Aure, Miriam Ragle +7 more
core +2 more sources
Overexpression of microRNA-630 in Acute Leukemic T-cell line [PDF]
, 2020 Background: MicroRNAs (miRNAs) are noncoding RNAs that control the expression of their target mRNAs. It affects cancer cell proliferation and apoptosis as oncogenes or tumor suppressors.
Gharehdaghi, Z +3 more
core +1 more source
Molecular genetics of idiopathic pulmonary fibrosis
Вавиловский журнал генетики и селекции, 2022 Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic
R. N. Mustafin
doaj +1 more source
The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Stem Cell Research & Therapy, 2022 Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik +6 more
doaj +1 more source
MiR-10b alleviates high glucose-induced human retinal endothelial cell injury by regulating TIAM1 signaling [PDF]
, 2020 Purpose: To investigate the effects of microRNA (miR)-10b on high glucose (HG)-induced human retinal endothelial cell (HREC) injury and the mechanisms involved.Methods: Levels of miR-10b were measured in HRECs using quantitative reverse ...
Chen, Yaohua, Zhao, Sheng, Zhu, Yanqing
core +2 more sources
MicroRNAs in T Cell-Immunotherapy. [PDF]
, 2022 MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and disease. Despite the rapidly growing body of evidence on the theranostic potential of restoring miRNA levels in pre-clinical models, the translation into clinics remains ...
Dosil, Sara G +3 more
core +1 more source
Intratumoral heterogeneity of microRNA expression in rectal cancer [PDF]
, 2016 Introduction: An increasing number of studies have investigated microRNAs (miRNAs) as potential markers of diagnosis, treatment and prognosis.
A Esquela-Kerscher +34 more
core +5 more sources
Veterinary Research, 2020 Marek’s disease (MD) is a contagious disease of domestic chickens caused by MD viruses. MD has been controlled primarily by vaccinations, yet sporadic outbreaks of MD take place worldwide.
Lei Zhang +6 more
doaj +1 more source
Noncoding RNAs as Predictive Biomarkers of Therapeutic Response to Tyrosine Kinase Inhibitors in Metastatic Cancer [PDF]
, 2019 Since their discovery, noncoding RNAs have acquired extensive attention due to their eminent role in the regulation of gene expression and thus also in the pathogenesis of many diseases.
Kovacova, Julia, Slaby, Ondrej
core +2 more sources