Results 41 to 50 of about 340,399 (164)

Gefitinib and luteolin cause growth arrest of human prostate cancer PC-3 cells via inhibition of cyclin G-associated kinase and induction of miR-630.

open access: yesPLoS ONE, 2014
Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostate ...
Minami A Sakurai   +11 more
doaj   +1 more source

[Retracted] MicroRNA‑143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer

open access: yesMolecular Medicine Reports, 2023
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that several of the panels showing the results from cell migration and invasion assay experiments in Fig. 2 on p.
Deyao Wu   +5 more
semanticscholar   +1 more source

CHO microRNA engineering is growing up : recent successes and future challenges [PDF]

open access: yes, 2013
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes   +12 more
core   +1 more source

Bioinformatic analysis of the ssc-miR-146b upstream promoter region

open access: yesAnimal Nutrition, 2015
Sus Scrofa microRNA-146b-5p (ssc-miR-146b) was found to be one of differentially expressional microRNAs (miRNA) in our previous study. Not only it is highly expressed but also it maintains the largest up-regulated differences on the expressional level at
Xin Tao, Xiaoming Men, Ziwei Xu
doaj   +1 more source

Plasma extracellular vesicle microRNA‐491‐5p as diagnostic and prognostic marker for head and neck squamous cell carcinoma

open access: yesCancer Science, 2021
Poor survival of patients with locally advanced head and neck squamous cell carcinoma (LA‐HNSCC) is partly due to early diagnosis difficulties and the lack of reliable biomarkers for predicting treatment outcomes.
W. Panvongsa   +7 more
semanticscholar   +1 more source

Down-regulation of microRNA-125b-2-3p is a risk factor for a poor prognosis in hepatocellular carcinoma

open access: yesBioengineered, 2021
Hepatocellular carcinoma (HCC) is a leading cause of mortality in cancer patients, but the association between miR-125b-2-3p and the onset and prognosis of HCC has not been reported in previous studies; thus, the clinicopathological implications of miR ...
He-Qing Huang   +9 more
semanticscholar   +1 more source

Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]

open access: yes, 2014
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A.   +3 more
core   +1 more source

Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]

open access: yes, 2015
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A   +23 more
core   +1 more source

MicroRNA expression profile predicts prognosis of pediatric adrenocortical tumors

open access: yesPediatric Blood & Cancer, 2021
Pediatric adrenocortical tumors (ACT) are rare aggressive neoplasms with heterogeneous prognosis. Despite extensive efforts, identifying reliable prognostic factors for pediatric patients with ACT remains a challenge.
L. Veronez   +16 more
semanticscholar   +1 more source

Characterisation of body fluid specific microRNA markers by capillary electrophoresis [PDF]

open access: yes, 2013
The characterisation of RNA molecules for the purpose of body fluid identification is currently a major field in forensic genetics; with a great deal of effort going towards the analysis of messenger RNA (mRNA).
World, Damien   +6 more
core   +1 more source

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