Results 41 to 50 of about 1,313,156 (149)

Retraction: Circular RNA‐0007874 (circMTO1) reverses chemoresistance to temozolomide by acting as a sponge of microRNA‐630 in glioblastoma by Jiang Rao, Xinxin Cheng, Huimin Zhu, Lifeng Wang, Li Liu [PDF]

Cell Biology International, 2019
The above article, published online on 11 December 2018 in Wiley Online Library ( https://doi.org/10.1002/cbin.11080 ), has been withdrawn by agreement with the journal Editor, Sergio Schenkman, and John Wiley & Sons Ltd.
openaire   +1 more source

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications

AGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, Volume 13, Issue 57, 14 October 2026.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Considering the effect of stem-loop reverse transcription and quantitative PCR analysis of blood and saliva specific microRNA markers upon mixed body fluid stains [PDF]

, 2013
Forensic RNA analysis is gathering pace with reports of messenger RNA analysis being used in case work, and with microRNA being increasingly researched.
Uchimoto, M.L., Coult, N., Omelia, E.J., Beasley, E., Williams, Graham, Coult, Natalie, World, Damian, World, D., Omelia, Emma J., Uchimoto, Mari L., Beasley, Emma   +10 more
core   +1 more source

Interplay Between Epigenetics and Reactive Oxygen Species in Tumor Radioresistance: Mechanisms and Therapeutic Strategies for Radiotherapy

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Radiotherapy efficacy is constrained by tumor radioresistance, which arises in part from the interplay between reactive oxygen species (ROS) and epigenetic regulation. This review systematically synthesizes the bidirectional “epigenetics‐ROS interactive network” that governs tumor radiosensitivity. We propose that this network operates through
Zhengmao Yang, Jiaxin Wang, Guofang Wang, Jiamin Zhu, Shengnan Zhang, Wenjian Guo   +5 more
wiley   +1 more source

miREE: miRNA Recognition Elements Ensemble [PDF]

, 2011
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii, Acquaviva, Andrea, Paula H Reyes-Herrera, Macii Enrico, Acquaviva Andrea, REYES HERRERA, PAULA HELENA, Andrea Acquaviva, Elisa Ficarra, Ficarra, Elisa, Reyes-Herrera Paula H, Macii, Enrico, Ficarra Elisa, Reyes Herrera Ph   +12 more
core   +1 more source

Human biomarker navigator

iMeta, Volume 5, Issue 5, October 2026.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Annexin V‐Functionalized Injectable Calcium‐Deficient Hydroxyapatite for Extracellular Vesicles Binding and Controlled Release

Journal of Biomedical Materials Research Part A, Volume 114, Issue 10, October 2026.
ABSTRACT Calcium phosphates alone have a limited induction potential in challenging bone conditions, necessitating strategies that enhance cellular responses and matrix‐related processes. An injectable formulation combining calcium‐deficient hydroxyapatite (CDHA) with mesenchymal stem cell‐derived extracellular vesicles may present a promising approach
Eda Ciftci, Sefa Burak Cam, Feza Korkusuz, Emre Erdem, Feray Bakan Misirlioglu, Petek Korkusuz   +5 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, Volume 20, Issue 9, Page 2220-2242, September 2026.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source