PLoS ONE, 2014 Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostate ...
Minami A Sakurai +11 more
doaj +1 more source
CHO microRNA engineering is growing up : recent successes and future challenges [PDF]
, 2013 microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes +12 more
core +1 more source
Bioinformatic analysis of the ssc-miR-146b upstream promoter region
Animal Nutrition, 2015 Sus Scrofa microRNA-146b-5p (ssc-miR-146b) was found to be one of differentially expressional microRNAs (miRNA) in our previous study. Not only it is highly expressed but also it maintains the largest up-regulated differences on the expressional level at
Xin Tao, Xiaoming Men, Ziwei Xu
doaj +1 more source
Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]
, 2014 MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A. +3 more
core +1 more source
Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]
, 2015 Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A +23 more
core +1 more source
Genetics and Molecular Research, 2015 MicroRNAs (miRNAs) are a family of small non-coding RNAs (approximately 21-23 nt long) that can target genes for either degradation of mRNA or inhibition of translation. miRNAs have not been comprehensively studied in human epithelial ovarian carcinoma (EOC).
Y T, Zou +5 more
openaire +2 more sources
Considering the effect of stem-loop reverse transcription and quantitative PCR analysis of blood and saliva specific microRNA markers upon mixed body fluid stains [PDF]
, 2013 Forensic RNA analysis is gathering pace with reports of messenger RNA analysis being used in case work, and with microRNA being increasingly researched.
Uchimoto, M.L. +10 more
core +1 more source
Characterisation of body fluid specific microRNA markers by capillary electrophoresis [PDF]
, 2013 The characterisation of RNA molecules for the purpose of body fluid identification is currently a major field in forensic genetics; with a great deal of effort going towards the analysis of messenger RNA (mRNA).
World, Damien +6 more
core +1 more source
microRNA-mRNA pairs with a significant inverse correlation in vulvar melanoma. [PDF]
, 2023 microRNA-mRNA pairs with a significant inverse correlation in vulvar melanoma.
Colin D. Angell (16469560) +14 more
core +1 more source
Body fluid mixtures; resolution using forensic microRNA analysis [PDF]
, 2013 Body fluid identification is a crucial aspect of forensic biology; particularly in sexual assaults which is usually characterised as a mixture of body fluids.
World, Damien +5 more
core +1 more source