Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Impact of Perioperative Proton Pump Inhibitors on Renal Cancer Progression. A Retrospective Study
ABSTRACT Background Clear cell renal cell carcinoma (ccRCC) is the most common kidney cancer. Metastatic disease causes most deaths. We investigated the association between ATP4A gene status and survival following nephrectomy. ATP4A encodes H+/K+ ATPase, targeted by proton pump inhibitors (PPIs).
Nicolas Cortes‐Mejia +6 more
wiley +1 more source
Both transient ischaemic attack (TIA) and ischaemic stroke lead to an increase in individual cellular‐derived populations of extracellular vesicles (EVs), including endothelial, platelet and leukocyte derived. These EVs have downstream roles in the pathophysiological events associated with TIA and stroke, including dysregulated inflammation and ...
Rebecca Marie Raven +3 more
wiley +1 more source
Differential loading of the Argonaute complex in Epstein-Barr Virus (EBV)-infected cell lines derived from diffuse large B-cell lymphoma (DLBCL) [PDF]
MicroRNAs sind essentielle post-transkriptionelle Regulatoren der Genexpression die an unterschiedlichen Prozessen wie Entwicklung, Signaltransduktion oder Wachstumskontrolle durch Bindung und Inhibition der Translation ihrer mRNA Ziel mRNAs beteiligt ...
Ayoubian, Mohammad Hiresh
core +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
ABSTRACT MicroRNAs (miRNAs) have been shown to regulate many cellular processes and to play a role in host‐pathogen interactions. However, the role of miRNA in urinary tract infection (UTI) remains unclear. The aim of this study was to analyze and compare miRNAs from supernatants of human bladder epithelial cells infected with ESBL‐producing (ESBL019 ...
Katarina Persson +3 more
wiley +1 more source
The role of Fusobacterium nucleatum in macrophage M2 polarization and NF-κB pathway activation in colorectal cancer [PDF]
Fusobacterium nucleatum is strongly linked to colorectal cancer (CRC) progression, but its mechanisms for influencing macrophage polarization and tumor development are not well understood. We established an in vitro model of F.
Chunshan Quan +11 more
core +1 more source
Investigation of Circular RNA Regulation by Cis and Trans Elements in Caenorhabditis Elegans [PDF]
Circular RNAs (circRNAs) are regulatory molecules that show diverse functions. However, the regulation of circRNA formation is not yet well-understood. Through large-scale neuron isolation from the first larval stage of Caenorhabditis elegans followed by
Dong Cao
core +1 more source
Microbial metabolites in tumor epigenetic regulation
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression
ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao +4 more
wiley +1 more source

