MicroRNA-200b expression level is negatively associated with pathological grading in human gliomas
Xiangyi Kong,1,2,* Shun Gong,3–5,* Tao Yan,6,* Yi Yang1 1Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, People’s Republic of China; 2Department of Breast Surgical ...
Kong X, Gong S, Yan T, Yang Y
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The underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma [PDF]
The consistent notion holds that hepatocellular carcinoma (HCC) initiation, progression, and clinical treatment failure treatment failure are affected by the accumulation of various genetic and epigenetic alterations.
Fuguo He +3 more
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MOLECULAR DETERMINANTS OF RESIDUAL DISEASE IN OVARIAN CANCER [PDF]
The standard treatment for high grade serous ovarian cancer is primary cytoreductive surgery followed by adjuvant chemotherapy. Residual disease followed by surgery is associated with adverse overall and progression-free survival as well as poor response
Gharpure, Kshipra M
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Analysis of miRNAs in HPV-associated carcinomas [PDF]
Papilomaviry jsou malé DNA viry, které jsou spojovány s indukcí epiteliálních nádorů. HPV je známý jako infekční agens způsobující téměř 100 % nádorů cervixu, ale může být též původcem karcinomů v dalších místech anogenitálního traktu či nádorů hlavy a ...
Pagáčová, Lucie
core
The Human ARF Tumor Suppressor Regulates Drosha Nucleolar Localization and rRNA Processing Activity [PDF]
Ribosomes are vital to the survival of a cell, as they are directly responsible for the synthesis of proteins, which perform critical cellular functions.
Yaddanapudi, Sree Chandana Sridhar
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Analysis of HPV16 Variants in the Carolina Women’s Care Study and a Comparison of Gene Expression Profiles of Exfoliated Cervical Cells From Women Who Either Clear or Do Not Clear an HPV16 Infection [PDF]
Human papillomavirus (HPV) is the etiologic agent for cervical cancer with HPV type 16 (HPV16) being found in about 50% of cervical cancers worldwide. HPVs vary in genomic (DNA) sequence not only between types, but also within types, known as variants ...
Green, Erica Shirlene
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Investigating functional effects of microRNAs contained in extracellular vesicles from Natural Killer cells [PDF]
Natural Killer (NK) cells are lymphocytes that secrete cytotoxic extracellular vesicles (EVs), which are being investigated for their anti-cancer properties and therapeutic potential.
Hagen, Tirill Marie Trøften Hagen
core
Understanding the role of miRNA expression in the differentiation of haematopoietic stem cells from pluripotent stem cells [PDF]
PhD ThesisHematopoietic diseases such as leukaemia can be treated by a haematopoietic stem cell transplant, but suitable donors are in short supply. Hematopoietic cells derived from pluripotent stem cells have been suggested as a possible alternative ...
Meader, Eleanor Synnove
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Bacterial and tissue biomarkers of gastric cancer: new findings and future perspectives: review article [PDF]
Gastric cancer (GC) is the second leading cause of cancer-related deaths worldwide. It has been proposed that the specific genotypes of Helicobacter pylori (H.
زهری, صابر +4 more
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Characterization of the DNA methylation patterns of chemosensitive and chemoresistant human cancer cells: Biological and clinical impact [PDF]
[spa] La quimioresistencia es el principal limitante para el tratamiento del paciente oncológico. La comprensión de los mecanismos celulares que conducen a la quimioresistencia puede tener un impacto drástico en la utilización de los fármacos.
Moutinho, Cátia
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