Results 71 to 80 of about 340,399 (164)

MicroRNA‐Mediated Regulation of Brain Aging Hallmarks: Implications for Neurodegeneration and Neural Recovery

Brain and Behavior, Volume 16, Issue 5, May 2026.
Hallmarks of brain aging regulated by microRNAs (miRNAs). This graphical abstract illustrates the central role of miRNAs in coordinating key biological processes associated with brain aging. miRNAs regulate multiple interconnected hallmarks, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis and impaired ...
Mustafa T. Ardah, Pareshkumar N. Patel, Omayma Salim Waleed, Jamuna K. V., Vandana Tripathi, L. Lakshmi, Rajashree Panigrahi, Manoj Kumar Mishra   +7 more
wiley   +1 more source

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

British Journal of Haematology, Volume 208, Issue 5, Page 1535-1550, May 2026.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu, Jui‐Feng Hsu, Jee‐Fu Huang, Yi‐Chang Liu   +3 more
wiley   +1 more source

Bibliometric analysis of mucosal immunity in IgA nephropathy from 1990 to 2022

Immunity, Inflammation and Disease
Objective The study aimed to conduct a bibliometric analysis of mucosal immunity in IgA nephropathy (IgAN) and indicate its current status, hot sopts, and direction of future studies. Methods The literature data was collected from the Web of Science Core
Xian Chen, Zhe Yan, Qing Pan, Chunxia Zhang, Yakun Chen, Xuzhi Liang, Shaomei Li, Gang Wu   +7 more
doaj   +1 more source

The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat Triticum turgidum cv Kronos

New Phytologist, Volume 250, Issue 3, Page 1389-1410, May 2026.
Summary Triticum turgidum cv Kronos is a tetraploid wheat cultivar that underpins one of the most widely used community platforms for functional genomics. Over the past decade, researchers have generated c. 3000 exome‐capture (EC) and promoter‐capture (PC) datasets linked to mutagenized seed stocks, along with extensive transcriptomic and phenotypic ...
Kyungyong Seong, Rakesh Kumar, Daniil M. Prigozhin, China Lunde, Thales Henrique Cherubino Ribeiro, Sébastien Bélanger, Jo‐Wei Allison Hsieh, McCree Tang, Blake C. Meyers, Ksenia V. Krasileva   +9 more
wiley   +1 more source

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]

, 2012
Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Oak, Prajakta S., Prajakta S. Oak (115995), Florian Kopp, Andreas Roidl, Kopp, Florian, Roidl, Andreas, Prajakta S Oak, Florian Kopp (115988), Ernst Wagner (60760), Andreas Roidl (116002), Wagner, Ernst, Ernst Wagner   +11 more
core   +1 more source

SBP‐Box Transcription Factor JcSPL9 Regulates Both Seed Yield and Oil Content in the Biofuel Plant Jatropha curcas

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3125-3140, May 2026.
ABSTRACT Jatropha curcas is a promising feedstock for biodiesel and bio‐jet fuels production; however, its seed yield is constrained by limited inflorescences. SPL9 is a member of the SBP‐box gene family that promotes the juvenile‐to‐adult phase transition.
Mingyong Tang, Xue Bai, Yaoping Xia, Ping Huang, Zeng‐Fu Xu   +4 more
wiley   +1 more source

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

Photochemistry and Photobiology, Volume 102, Issue 3, Page 625-638, May/June 2026.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard, Meghan M. Dillon, Lauren A. Sapienza‐Lundie, Suzanne E. Fenton, Imran Rizvi   +4 more
wiley   +1 more source

Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma

, 2011
Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies ...
Polta, Andreas, Kronenberger, Bernd, Peveling-Oberhag, Jan, Bernd Kronenberger, Haupenthal Jörg, Susser, Simone, Andreas Polta, Susser Simone, Welker, Martin, Piiper, Albrecht, Trojan Jörg, Jörg Trojan, Forestier, Nicole, Radeke, Heinfried H., Peveling-Oberhag Jan, Heinfried H Radeke, Verena Bihrer, Jan Peveling-Oberhag, Heinfried H. Radeke, Welker, Martin-Walter, Polta Andreas, Radeke Heinfried H., Nicole Forestier, von Wagner Michael, Kronenberger Bernd, Stefan Zeuzem, Friedrich-Rust Mireen, Oliver Waidmann, Friedrich-Rust, Mireen, Michael von Wagner, Sarrazin, Christoph, Radeke, Heinfried H, Zeuzem Stefan, Christoph Sarrazin, Martin Welker, Shi Ying, Jörg Haupenthal, von Wagner, Michael, Simone Susser, Forestier Nicole, Piiper Albrecht, Bihrer Verena, Bihrer, Verena, Haupenthal, Jörg, Welker Martin, Sarrazin Christoph, Shi, Ying, Peveling-Oberhag, Jan Franz-Josef, Mireen Friedrich-Rust, Waidmann Oliver, Waidmann, Oliver, Albrecht Piiper, Trojan, Jörg, Ying Shi, Wagner, Michael von, Zeuzem, Stefan   +55 more
core   +1 more source

MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation [PDF]

, 2014
This work was funded by the Multiple Sclerosis Society. Tissue samples and associated clinical and neuropathological data were supplied by the UK MS Tissue ...
Kay, O., Reijerkerk, A., Hirst, MC, King-Robson, Josh, de Vries, HE, Michael, G.J., Male, DK, Reijerkerk, A, Reijerkerk, Arie, Sharrack, B, de Vries, Helga E., Romero, I.A., Baker, D., Kay, Oliver, Simpson, Julie E., Simpson, J.E., Romero, IA, Male, D.K., de Vries, H.E., Baker, David, King-Robson, J., Sharrack, B., King-Robson, J, Wu, D., Michael, GJ, Wu, Dongsheng, Wu, D, Simpson, JE, Lopez-Ramirez, Miguel Alejandro, Lopez-Ramirez, MA, Kay, O, Pryce, Gareth, Hirst, M.C., Baker, D, Male, David Kingsley, Romero, Ignacio Andres, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +41 more
core   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, Volume 5, Issue 2, April 2026.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source