Results 51 to 60 of about 108,740 (146)

Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]

, 2009
Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
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MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul, Przemyslaw A Stempor, Paul Wilson, Cauchi, Michael, Michael Cauchi, Stempor, Przemyslaw A.   +5 more
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Retraction: Circular RNA‐0007874 (circMTO1) reverses chemoresistance to temozolomide by acting as a sponge of microRNA‐630 in glioblastoma by Jiang Rao, Xinxin Cheng, Huimin Zhu, Lifeng Wang, Li Liu [PDF]

Cell Biology International, 2019
The above article, published online on 11 December 2018 in Wiley Online Library ( https://doi.org/10.1002/cbin.11080 ), has been withdrawn by agreement with the journal Editor, Sergio Schenkman, and John Wiley & Sons Ltd.
openaire   +1 more source

miREE: miRNA Recognition Elements Ensemble [PDF]

, 2011
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii, Acquaviva, Andrea, Paula H Reyes-Herrera, Macii Enrico, Acquaviva Andrea, REYES HERRERA, PAULA HELENA, Andrea Acquaviva, Elisa Ficarra, Ficarra, Elisa, Reyes-Herrera Paula H, Macii, Enrico, Ficarra Elisa, Reyes Herrera Ph   +12 more
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Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma [PDF]

, 2011
Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies ...
Polta, Andreas, Kronenberger, Bernd, Peveling-Oberhag, Jan, Bernd Kronenberger, Haupenthal Jörg, Susser, Simone, Andreas Polta, Susser Simone, Welker, Martin, Piiper, Albrecht, Trojan Jörg, Jörg Trojan, Forestier, Nicole, Radeke, Heinfried H., Peveling-Oberhag Jan, Heinfried H Radeke, Verena Bihrer, Jan Peveling-Oberhag, Heinfried H. Radeke, Welker, Martin-Walter, Polta Andreas, Radeke Heinfried H., Nicole Forestier, von Wagner Michael, Kronenberger Bernd, Stefan Zeuzem, Friedrich-Rust Mireen, Oliver Waidmann, Friedrich-Rust, Mireen, Michael von Wagner, Sarrazin, Christoph, Radeke, Heinfried H, Zeuzem Stefan, Christoph Sarrazin, Martin Welker, Shi Ying, Jörg Haupenthal, von Wagner, Michael, Simone Susser, Forestier Nicole, Piiper Albrecht, Bihrer Verena, Bihrer, Verena, Haupenthal, Jörg, Welker Martin, Sarrazin Christoph, Shi, Ying, Peveling-Oberhag, Jan Franz-Josef, Mireen Friedrich-Rust, Waidmann Oliver, Waidmann, Oliver, Albrecht Piiper, Trojan, Jörg, Ying Shi, Wagner, Michael von, Zeuzem, Stefan   +55 more
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Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

A robust system for RNA interference in the chicken using a modified microRNA operon [PDF]

, 2006
RNA interference (RNAi) provides an effective method to silence gene expression and investigate gene function. However, RNAi tools for the chicken embryo have largely been adapted from vectors designed for mammalian cells.
Wilson, Stuart A, Placzek, Marysia, Sacco, Melanie A., Sang, Helen M, McGrew, Michael J., Howell, Gareth R., Van Hateren, Nick J., Porteous, Victoria C, Manning, Elizabeth M, Porteous, Victoria C., Bangs, Fiona K, Bangs, Fiona K., Sacco, Melanie A, Nair, Venugopal K, Das, Raman M, McGrew, Mike; id_orcid, Das, Raman M; id_orcid, Van Hateren, Nick J, Storey, Kate G, Tickle, Cheryll, Farrell, Elizabeth R, Storey, Kate G., Wilson, Stuart A., Farrell, Elizabeth R., Halley, Pam A, Das, Raman M., Sang, Helen M., Howell, Gareth R, Manning, Elizabeth M., McGrew, Michael J, Ohyama, Kyoji, Nair, Venugopal K., Halley, Pam A.   +32 more
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Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

“MicroRNA Expression Profiling in human Subcutaneous Adipose Tissue” [PDF]

, 2008
MicroRNA are believed to be generally involved in more quantitative regulation of mammalian trait: therefore, mammalian conditions that have a strong genetic component and involve quantitative differences between the physiological and pathological ...
Castanò, Ilenia
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