Results 31 to 40 of about 1,313,156 (149)

miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer

Molecular Cancer, 2014
Background While the treatment of HER2 over-expressing breast cancer with recent HER-targeted drugs has been highly effective for some patients, primary (also known as innate) or acquired resistance limits the success of these drugs.
Claire Corcoran, Sweta Rani, Susan Breslin, Martina Gogarty, Irene M Ghobrial, John Crown, Lorraine O’Driscoll   +6 more
doaj   +1 more source

Bioinformatic analysis of the ssc-miR-146b upstream promoter region

Animal Nutrition, 2015
Sus Scrofa microRNA-146b-5p (ssc-miR-146b) was found to be one of differentially expressional microRNAs (miRNA) in our previous study. Not only it is highly expressed but also it maintains the largest up-regulated differences on the expressional level at
Xin Tao, Xiaoming Men, Ziwei Xu
doaj   +1 more source

Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]

, 2014
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A., Dunnett, Hannah, Williams, Graham, Van der Meer, Dieudonne   +3 more
core   +1 more source

Downregulation of microRNA-630 inhibits cell proliferation and invasion and enhances chemosensitivity in human ovarian carcinoma

Genetics and Molecular Research, 2015
MicroRNAs (miRNAs) are a family of small non-coding RNAs (approximately 21-23 nt long) that can target genes for either degradation of mRNA or inhibition of translation. miRNAs have not been comprehensively studied in human epithelial ovarian carcinoma (EOC).
Y T, Zou, J Y, Gao, H L, Wang, Y, Wang, H, Wang, P L, Li   +5 more
openaire   +2 more sources

microRNA-630 promotes cell proliferation and inhibits apoptosis in the HCT116 human colorectal cancer cell line

Molecular Medicine Reports, 2017
Dysregulation of microRNAs (miRNAs) in colorectal cancer provides important opportunities for the development of future miRNA‑based therapies. The present study aimed to assess the role of miRNA‑630 (miR‑630) expression in colorectal cancer. HCT116 human colorectal cancer cells were transfected with miR‑630 inhibitor, mimic or control miRNA, and the ...
Lijuan, Zhang, Gang, Feng, Xinyan, Zhang, Yawen, Ding, Xiaojuan, Wang   +4 more
openaire   +3 more sources

microRNA-mRNA pairs with a significant inverse correlation in vulvar melanoma.

, 2023
microRNA-mRNA pairs with a significant inverse correlation in vulvar melanoma.
Colin D. Angell (16469560), William E. Carson III (11372435), Alejandro A. Gru (11372432), Casey Ren (15179108), Maribelle Moufawad (11372429), Mallory J. DiVincenzo (11372420), Catherine Chung (680172), Floor J. Backes (16469563), Kari Ring (16469566), Zoe Barricklow (11372423), Paolo Fadda (765567), Anne Mills (70199), Craig Slingluff (4399051), Lorena P. Suarez-Kelly (11552092), Lianbo Yu (144585)   +14 more
core   +1 more source

CHO microRNA engineering is growing up : recent successes and future challenges [PDF]

, 2013
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes, Heffner, Kelley M., Shridhar, Smriti, Borth, Nicole, Barron, Niall, Betenbaugh, Mike, Shiloach, Joseph, Chung, Cheng-Yu, Hackl, Matthias, Kreil, David, Jadhav, Vaibhav, Druz, Aliaksandr   +11 more
core   +1 more source

“MicroRNA Expression Profiling in human Subcutaneous Adipose Tissue” [PDF]

, 2008
MicroRNA are believed to be generally involved in more quantitative regulation of mammalian trait: therefore, mammalian conditions that have a strong genetic component and involve quantitative differences between the physiological and pathological ...
Castanò, Ilenia
core   +1 more source

microRNA-767 and its binding site polymorphism in mTOR gene act as potential biomarkers for female reproductive cancers - supplementary material

, 2023
Supplementary Table 1: Demographic and histopathological parameters of cases and controls.Supplementary Table 2: Primers for microRNA-767, U6 and Tetra-ARMS PCR primers for mTOR(rs2536) SNPSupplementary Table 3: PCR conditions for tetra arms ...
Ishrat Mahjabeen (846545), Kashaf Bibi (17079994), Nida Sarosh Ashraf (17080000), Maria Fazal Ul Haq (17080003), Mahmood Akhtar Kayani (783301), Azhar Mehmood (12966920), Rabia Shafique (14659740), Sumaira Fida Abbasi (17080006), Nadia Saeed (12966914), Muhammad Rizwan (536386), Farah Kalsoom (17079997)   +10 more
core   +1 more source

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival [PDF]

, 2011
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Hatton, CSR, Taylor Steve, Taylor, Stephen, Taylor, S, Lawrie Charles H, Saunders, NJ, Steve Taylor, Pezzella Francesco, Saunders Nigel J, Tramonti, D, Lawrie, CH, Wainscoat James S, Kusec, R, Pezzella, F, Tramonti Daniela, Nigel J Saunders, Hatton Christian SR, Chen, XH, Hatton, CS, Charles H Lawrie, Rajko Kušec, Littlewood, T, Erica Ballabio, Deborah Hay, Timothy Littlewood, Chi, J, Jacqueline Boultwood, Boultwood Jacqueline, Kušec Rajko, Jianxiang Chi, Chen Xiao-He, James S Wainscoat, Ballabio, E, Ballabio Erica, Chi Jianxiang, Xiao-He Chen, Littlewood Timothy, Francesco Pezzella, Christian SR Hatton, Wainscoat, JS, Hay Deborah, Pezzella, Francesco, Boultwood, Jacqueline, Hay, D, Boultwood, J, Daniela Tramonti   +45 more
core   +1 more source