Molecular genetics of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic
R. N. Mustafin
doaj +1 more source
Overexpression of microRNA-630 in Acute Leukemic T-cell line [PDF]
Background: MicroRNAs (miRNAs) are noncoding RNAs that control the expression of their target mRNAs. It affects cancer cell proliferation and apoptosis as oncogenes or tumor suppressors.
Yasuj, S.R +3 more
core +1 more source
The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik +6 more
doaj +1 more source
MicroRNA-630 is a prognostic marker for patients with colorectal cancer
MicroRNAs are noncoding RNAs that regulate multiple cellular processes during cancer progression. Among various microRNAs, miR-630 has recently been identified to be implicated in many critical processes in human malignancies. We investigated the expression pattern and prognostic value of miR-630 in human colorectal cancer by utilizing cancer and ...
Dake, Chu +7 more
openaire +2 more sources
RNAhybrid: microRNA target prediction easy, fast, and flexible [PDF]
Krüger J, Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast, and flexible. Nucleic Acids Research.
Krüger, Jan, Rehmsmeier, Marc
core +1 more source
Comprehensive prediction of novel microRNA targets in Arabidopsis thaliana [PDF]
Alves jun. L, Niemeier S, Hauenschild A, Rehmsmeier M, Merkle T. Comprehensive prediction of novel microRNA targets in Arabidopsis thaliana. Nucleic Acids Research.
Ra Niemeier +10 more
core +2 more sources
MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Hatton, CSR +45 more
core +1 more source
Decoding transcription and microRNA-mediated translation control in Drosophila development [PDF]
The spatio-temporal regulation of gene expression lies at the heart of animal development. In this article we present an overview of our recent work to apply systems biological approaches to the study of transcription and microRNA-mediated translation ...
Gaul, Ulrike
core +1 more source
CHO microRNA engineering is growing up : recent successes and future challenges [PDF]
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes +12 more
core +1 more source
Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A. +3 more
core +1 more source

