Results 31 to 40 of about 3,995 (136)
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach [PDF]
, 2023 Background: Cancer-associated fibroblasts (CAFs) of ovarian cancer (OvC) are the most prevalent element of the tumor microenvironment (TM). By promoting angiogenesis, immunological suppression, and invasion, CAFs speed up the growth of tumors by changing
Abolfazl Bahrami +13 more
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PLoS ONE, 2014 Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostate ...
Minami A Sakurai +11 more
doaj +1 more source
Primary and recurrent ovarian high-grade serous carcinomas display similar microRNA expression patterns relative to those of normal ovarian tissue [PDF]
, 2017 Most patients with epithelial ovarian cancer eventually die due to recurrence. However, little is known about the microRNA (miRNA) expression pattern and its involvement in recurrent ovarian cancer.
김상운 +5 more
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Micro RNA facilitated chemoresistance in gastric cancer: a novel biomarkers and potential therapeutics [PDF]
, 2020 Introduction: In spite of the substantial advances in clinical practice, Gastric cancer (GC) remains the third leading cause of cancer death worldwide. The incidence of drug resistance remains a hindrance to effective treatment for GC.
Bhaskar, L. V. K. S. +4 more
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Bioinformatic analysis of the ssc-miR-146b upstream promoter region
Animal Nutrition, 2015 Sus Scrofa microRNA-146b-5p (ssc-miR-146b) was found to be one of differentially expressional microRNAs (miRNA) in our previous study. Not only it is highly expressed but also it maintains the largest up-regulated differences on the expressional level at
Xin Tao, Xiaoming Men, Ziwei Xu
doaj +1 more source
Molecular Medicine Reports, 2017 Dysregulation of microRNAs (miRNAs) in colorectal cancer provides important opportunities for the development of future miRNA‑based therapies. The present study aimed to assess the role of miRNA‑630 (miR‑630) expression in colorectal cancer. HCT116 human colorectal cancer cells were transfected with miR‑630 inhibitor, mimic or control miRNA, and the ...
Lijuan, Zhang +4 more
openaire +3 more sources
MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration [PDF]
, 2018 Alteration in microRNAs (miRNAs) expression is a frequent finding in human cancers. In particular, widespread miRNAs down-regulation is a hallmark of malignant transformation. In the present report, we showed that the miR-128-3p, which is up-regulated in
A. Sacconi +12 more
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Genetics and Molecular Research, 2015 MicroRNAs (miRNAs) are a family of small non-coding RNAs (approximately 21-23 nt long) that can target genes for either degradation of mRNA or inhibition of translation. miRNAs have not been comprehensively studied in human epithelial ovarian carcinoma (EOC).
Y T, Zou +5 more
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Role of miRNAs in Cancer [PDF]
, 2022 MicroRNAs are the best representatives of the non-coding part of the genome and their functions are mostly linked to their target genes. During the process of carcinogenesis, both dysregulation of microRNAs and their target genes can explain the ...
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MicroRNA and protein profiles in invasive versus non-invasive oral tongue squamous cell carcinoma cells in vitro [PDF]
, 2017 Complex molecular pathways regulate cancer invasion. This study overviewed proteins and microRNAs (miRNAs) involved in oral tongue squamous cell carcinoma (OTSCC) invasion.
Almangush, Alhadi +12 more
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