Results 1 to 10 of about 208,790 (267)
The clinical significance of circulating microRNA-21 in patients with IgA nephropathy [PDF]
Kosin Medical Journal, 2022 Background Urinary microRNA-21 (miR-21) has been reported to correlate with the histologic lesions of IgA nephropathy (IgAN). We investigated whether urinary or circulating miR-21 could serve as a biomarker for detecting the renal progression of IgAN ...
A Young Cho +3 more
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MicroRNA and Hemophilia-A Disease: Bioinformatics Prediction and Experimental Analysis [PDF]
Cell Journal, 2021 Objective: Hemophilia-A is a common genetic abnormality resulted from decreased or lack of factor VIII (FVIII) pro-coagulant protein function caused by mutations in the F8 gene.
Halimeh Rezaei +2 more
doaj +1 more source
Molecules, 2023 The anticarcinogenic potential of a series of 1,5-disubstituted tetrazole-1,2,3-triazole hybrids (T-THs) was evaluated in the breast cancer (BC)-derived cell lines MCF-7 (ER+, PR+, and HER2−), CAMA-1 (ER+, PR+/−, and HER2−), SKBR-3 (ER+, PR+, and HER2+),
Marisol Moreno-Perea +10 more
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Journal of Medical Microbiology and Infectious Diseases, 2021 Introduction. Helicobacter pylori infection is one of the primary etiological factors associated with gastric carcinogenesis. This study investigated the expression of microRNAs, miR-20a, miR-30a, miR-210, and miR-874, in H.
Saba Hariri Monfared1 +3 more
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Molecules, 2020 We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and ...
Sergio Córdova-Rivas +9 more
doaj +1 more source
Potential of melatonin to reverse epigenetic aberrations in oral cancer
EXCLI Journal : Experimental and Clinical Sciences, 2023 It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis and functional changes, both of which are essential for the initiation and completion of the tumor cycle.
Emilio Gil-Martín +4 more
doaj +1 more source
Probable Mechanisms of COVID-19 Pathogenesis
Креативная хирургия и онкология, 2020 This review paper focuses on the search for innovative directions in the study of COVID19 viral infection with the purpose of improving the methods of its treatment and vaccination.
R. N. Mustafin, E. K. Khusnutdinova
doaj +1 more source
Journal of Obesity & Metabolic Syndrome, 2023 Background : Growth differentiation factor-15 (GDF-15) is involved in insulin resistance and diabetes. In this study, we determine the associations of GDF-15 with miR-181b-5p, miR-330-3p, mothers against decapentaplegic homolog 7 (SMAD7), and insulin ...
Dipayan Roy +7 more
doaj +1 more source
miR-802-5p is a key regulator in diabetic kidney disease
Journal of Research in Medical Sciences, 2023 Background: Diabetic kidney disease has substantial burden and limited therapeutic options. An inadequate understanding of the complex gene regulatory circuits underlying this disorder contributes to the insufficiency of current treatment strategies ...
Farnoush Kiyanpour +2 more
doaj +1 more source
Urinary exosomal microRNA profiling in type 2 diabetes patients taking dipeptidyl peptidase-4 inhibitor compared with sulfonylurea [PDF]
Kidney Research and Clinical Practice, 2021 Background Dipeptidyl peptidase-4 (DPP-4) inhibitor has been reported to have kidney-protective benefits. To elucidate how antidiabetic agents prevent diabetic kidney disease progression, it is important to investigate their effect on the kidney ...
Nam-Jun Cho +9 more
doaj +1 more source