Results 1 to 10 of about 282,884 (301)

The clinical significance of circulating microRNA-21 in patients with IgA nephropathy [PDF]

open access: yesKosin Medical Journal, 2022
Background Urinary microRNA-21 (miR-21) has been reported to correlate with the histologic lesions of IgA nephropathy (IgAN). We investigated whether urinary or circulating miR-21 could serve as a biomarker for detecting the renal progression of IgAN ...
A Young Cho   +3 more
doaj   +1 more source

MicroRNA and Hemophilia-A Disease: Bioinformatics Prediction and Experimental Analysis [PDF]

open access: yesCell Journal, 2021
Objective: Hemophilia-A is a common genetic abnormality resulted from decreased or lack of factor VIII (FVIII) pro-coagulant protein function caused by mutations in the F8 gene.
Halimeh Rezaei   +2 more
doaj   +1 more source

Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53

open access: yesMolecules, 2023
The anticarcinogenic potential of a series of 1,5-disubstituted tetrazole-1,2,3-triazole hybrids (T-THs) was evaluated in the breast cancer (BC)-derived cell lines MCF-7 (ER+, PR+, and HER2−), CAMA-1 (ER+, PR+/−, and HER2−), SKBR-3 (ER+, PR+, and HER2+),
Marisol Moreno-Perea   +10 more
doaj   +1 more source

Expression Analysis of MicroRNAs, miR-20a, miR-30a, miR-210, and miR-874 in Helicobacter pylori-infected patients with or without Gastric Cancer

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2021
Introduction. Helicobacter pylori infection is one of the primary etiological factors associated with gastric carcinogenesis. This study investigated the expression of microRNAs, miR-20a, miR-30a, miR-210, and miR-874, in H.
Saba Hariri Monfared1   +3 more
doaj   +1 more source

MicroRNA [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2018
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial regulators of gene expression and promising candidates for biomarker development.
Thomas X. Lu, Marc E. Rothenberg
openaire   +2 more sources

Differential Proliferation Effect of the Newly Synthesized Valine, Tyrosine and Tryptophan–Naphthoquinones in Immortal and Tumorigenic Cervical Cell Lines

open access: yesMolecules, 2020
We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and ...
Sergio Córdova-Rivas   +9 more
doaj   +1 more source

MicroRNA: MicroRNAs Reach out into Dendrites [PDF]

open access: yesCurrent Biology, 2006
A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Tai, H., Schuman, E.
openaire   +3 more sources

MicroRNA or Not MicroRNA? [PDF]

open access: yes, 2011
The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict with other ncRNAs, in particular snoRNAs.With few exceptions ...
David Langenberger   +5 more
openaire   +2 more sources

Novel expression of microRNAs in serum samples of Iraqi breast cancer women [PDF]

open access: yes, 2014
Although a lot of hard work against cancer to reduces its spread but it still continues to kill with abandon. The need for a biomarker for cancer early detection becomes the most mind concentrated scientists.
Jelawe, Majed   +5 more
core   +8 more sources

Potential of melatonin to reverse epigenetic aberrations in oral cancer

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis and functional changes, both of which are essential for the initiation and completion of the tumor cycle.
Emilio Gil-Martín   +4 more
doaj   +1 more source

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