Evaluation of the MiR-513a-5p Impinges on Progesterone Receptor Protein Expression in Breast Cancer Cells: A Systematic Review and Meta-analysis [PDF]
International Journal of Scientific Research in Dental and Medical Sciences, 2023 Background and aim: MicroRNAs can be considered as a predictor or cause of breast cancer. The present study was conducted to evaluate MiR-513a-5p's impacts on progesterone receptor protein expression in breast cancer cells.
Mahrokh Koochehbaghi +3 more
doaj +1 more source
Regulation of neutrophil senescence by microRNAs [PDF]
, 2011 Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer +60 more
core +5 more sources
Clusters of microRNAs emerge by new hairpins in existing transcripts [PDF]
, 2013 Genetic linkage may result in the expression of multiple products from a polycistronic transcript, under the control of a single promoter. In animals, protein-coding polycistronic transcripts are rare.
Alberts +66 more
core +2 more sources
Influence of sex differences on microRNA gene regulation in disease. [PDF]
, 2014 Sexual dimorphism is observed in most human diseases. The difference in the physiology and genetics between sexes can contribute tremendously to the disease prevalence, severity, and outcome.
Eghbali, Mansoureh, Sharma, Salil
core +1 more source
MicroRNAs and Metastasis [PDF]
Cancers, 2019 Metastasis, the development of secondary malignant growths at a distance from the primary site of a cancer, is associated with almost 90% of all cancer deaths, and half of all cancer patients present with some form of metastasis at the time of diagnosis. Consequently, there is a clear clinical need for a better understanding of metastasis.
Solé, Carla, Lawrie, Charles H.
openaire +2 more sources
Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7 [PDF]
, 2018 The excessive production of type I IFNs is a hallmark and a main pathogenic mechanism of many autoimmune diseases, including systemic lupus erythematosus (SLE).
Andreoli, Laura +9 more
core +1 more source
MicroRNAs in the Hypothalamus [PDF]
Neuroendocrinology, 2013 MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3′-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA ...
Meister, Björn +2 more
openaire +3 more sources
MicroRNAs as biomarkers in induced metabolic syndrome in rats [PDF]
Iraqi Journal of Veterinary SciencesMetabolic syndrome (Mets), consists of many clinical changes, such as dyslipidemia, obesity, resistance to insulin, and oxidative stress. It is become a global epidemic health problem.
Mutaa A. Al-Hayali +2 more
doaj +1 more source
High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing. [PDF]
, 2019 MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples.
Belair, Cassandra D +5 more
core +2 more sources
MicroRNAs in the stressed heart: Sorting the signal from the noise [PDF]
, 2014 The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Matkovich, Scot J
core +3 more sources