Results 21 to 30 of about 208,790 (267)

The microRNA Registry [PDF]

open access: yesNucleic Acids Research, 2004
The miRNA Registry provides a service for the assignment of miRNA gene names prior to publication. A comprehensive and searchable database of published miRNA sequences is accessible via a web interface (http://www.sanger.ac.uk/Software/Rfam/mirna/), and all sequence and annotation data are freely available for download.
openaire   +3 more sources

MicroRNA and cancer [PDF]

open access: yesMolecular Oncology, 2012
With the advent of next generation sequencing techniques a previously unknown world of non‐coding RNA molecules have been discovered. Non‐coding RNA transcripts likely outnumber the group of protein coding sequences and hold promise of many new discoveries and mechanistic explanations for essential biological phenomena and pathologies.
Jansson, Martin D, Lund, Anders H
openaire   +3 more sources

MicroRNA-26a-5p: multiple functions, multiple possibilities – a mini-review

open access: yesJournal of Pre-Clinical and Clinical Research, 2020
Introduction MicroRNA are small RNA molecules about 22 nucleotides long that do not encode proteins. Their function is to change the expression of proteins by attaching to their mRNA.
Paweł Zapolnik, Beata Zapolnik
doaj   +1 more source

Prediction of single-nucleotide polymorphisms within microRNAs binding sites of neuronal genes related to multiple sclerosis: A preliminary study

open access: yesAdvanced Biomedical Research, 2021
Background: Different genetic variants, including the single-nucleotide polymorphisms (SNPs) present in microRNA recognition elements (MREs) within 3'UTR of genes, can affect miRNA-mediated gene regulation and susceptibility to a variety of human ...
Reyhaneh Dehghanzad   +2 more
doaj   +1 more source

An Insight into Ocular Genetics

open access: yesDelhi Journal of Ophthalmology, 2017
Over the past decade, there has been an exponential increase in the database of heritable eye disorders. More than 100,000 germline mutations reported in more than 3,700 different human nuclear genes are associated with inherited diseases.
Shilpa Bisht   +3 more
doaj   +1 more source

Amniotic fetal stem cells – derived endothelial progenitors, a support for personalized cardiovascular regenerative medicine [PDF]

open access: yesArchives of the Balkan Medical Union, 2022
Introduction. Worldwide, cardiovascular diseases represent the first cause of morbidity and mortality. The genetic contribution in this pathology is heterogenous, and the microenvironment-genes interactions (mediated by epigenetic mechanisms) influence ...
Cosmin A. BUZILA, Florin IORDACHE
doaj   +1 more source

Predicting the possible effect of miR-203a-3p and miR-29a-3p on DNMT3B and GAS7 genes expression

open access: yesJournal of Integrative Bioinformatics, 2021
Aberrant expression of genes involved in methylation, including DNA methyltransferase 3 Beta (DNMT3B), can cause hypermethylation of various tumor suppressor genes.
Ali Afgar   +3 more
doaj   +1 more source

Establishment and Analysis of MicroRNA Prognostic Risk Model of Papillary Thyroid Carcinoma Based on TCGA Database

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To construct a risk model for predicting the prognosis of papillary thyroid carcinoma (PTC) patients based on the expression of microRNAs (miRNA).
JIAO Zhaoshuang, ZHANG Huainian
doaj   +1 more source

Circulating microRNA, secreted microRNA and exogenous plant microRNA [PDF]

open access: yesJournal of Translational Medicine, 2012
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves and horses.
openaire   +1 more source

MicroRNA-145-5p Regulates the Epithelial-Mesenchymal Transition in Nasal Polyps by Targeting Smad3 [PDF]

open access: yesClinical and Experimental Otorhinolaryngology
Objectives. The annual prevalence of chronic rhinosinusitis (CRS) is increasing, and the lack of effective treatments imposes a substantial burden on both patients and society.
Mengyu Zhang   +8 more
doaj   +1 more source

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