Results 11 to 20 of about 357,095 (308)

microRNA. Diagnostic Perspective [PDF]

open access: yesFrontiers in Medicine, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +6 more sources

Evaluation of the Potential of the MicroRNAs to Predict Chemotherapy Resistance in Breast Cancer Patients: A Systemic Review with Meta-analysis [PDF]

open access: yesInternational Journal of Scientific Research in Dental and Medical Sciences, 2023
Background and aim: Breast cancer is the most common cancer diagnosed in women. In predicting the survival rate of breast cancer patients, factors such as age, race, spread of the disease, stage of diagnosis, and involvement of lymph nodes are involved ...
Fatemeh Rabiee   +4 more
doaj   +1 more source

MicroRNA [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2018
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial regulators of gene expression and promising candidates for biomarker development.
Thomas X. Lu, Marc E. Rothenberg
  +5 more sources

Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53

open access: yesMolecules, 2023
The anticarcinogenic potential of a series of 1,5-disubstituted tetrazole-1,2,3-triazole hybrids (T-THs) was evaluated in the breast cancer (BC)-derived cell lines MCF-7 (ER+, PR+, and HER2−), CAMA-1 (ER+, PR+/−, and HER2−), SKBR-3 (ER+, PR+, and HER2+),
Marisol Moreno-Perea   +10 more
doaj   +1 more source

MicroRNA: MicroRNAs Reach out into Dendrites [PDF]

open access: yesCurrent Biology, 2006
A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Tai, H., Schuman, E.
openaire   +3 more sources

Role of retroelements in the development of COVID-19 neurological consequences

open access: yesRussian Open Medical Journal, 2022
Retroelements play a key role in brain functioning in humans and other animals, since they represent dynamic regulatory elements controlling the expression of specific neuron types.
Rustam N. Mustafin   +3 more
doaj   +1 more source

Differential Proliferation Effect of the Newly Synthesized Valine, Tyrosine and Tryptophan–Naphthoquinones in Immortal and Tumorigenic Cervical Cell Lines

open access: yesMolecules, 2020
We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and ...
Sergio Córdova-Rivas   +9 more
doaj   +1 more source

MicroRNA or Not MicroRNA? [PDF]

open access: yes, 2011
The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict with other ncRNAs, in particular snoRNAs.With few exceptions ...
Langenberger, David   +5 more
openaire   +2 more sources

MicroRNA therapeutics [PDF]

open access: yesGene Therapy, 2011
MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad roles in development and cellular processes make them fascinating to study. We still do not fully understand the molecular mechanisms by which miRNAs regulate gene expression nor do we know the complete repertoire of mRNAs each miRNA regulates.
Broderick, Jennifer A   +1 more
openaire   +3 more sources

The diagnostic value of circulating microRNAs as biomarkers for coronary artery disease: A meta‑analysis

open access: yesAnatolian Journal of Cardiology, 2020
Objective: In recent years, research on microRNAs (miRNAs) associated with coronary artery disease (CAD) has attracted considerable attention. However, findings of these studies on the validity of circulating miRNAs in CAD diagnosis are controversial.
Qin Fang   +5 more
doaj   +1 more source

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