An Insight into Ocular Genetics
Delhi Journal of Ophthalmology, 2017 Over the past decade, there has been an exponential increase in the database of heritable eye disorders. More than 100,000 germline mutations reported in more than 3,700 different human nuclear genes are associated with inherited diseases.
Shilpa Bisht +3 more
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Unique and conserved MicroRNAs in wheat chromosome 5D revealed by next-generation sequencing [PDF]
, 2013 MicroRNAs are a class of short, non-coding, single-stranded RNAs that act as post-transcriptional regulators in gene expression. miRNA analysis of Triticum aestivum chromosome 5D was performed on 454 GS FLX Titanium sequences of flow sorted chromosome 5D
Hikmet Budak (150694) +15 more
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Amniotic fetal stem cells – derived endothelial progenitors, a support for personalized cardiovascular regenerative medicine [PDF]
Archives of the Balkan Medical Union, 2022 Introduction. Worldwide, cardiovascular diseases represent the first cause of morbidity and mortality. The genetic contribution in this pathology is heterogenous, and the microenvironment-genes interactions (mediated by epigenetic mechanisms) influence ...
Cosmin A. BUZILA, Florin IORDACHE
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Predicting the possible effect of miR-203a-3p and miR-29a-3p on DNMT3B and GAS7 genes expression
Journal of Integrative Bioinformatics, 2021 Aberrant expression of genes involved in methylation, including DNA methyltransferase 3 Beta (DNMT3B), can cause hypermethylation of various tumor suppressor genes.
Ali Afgar +3 more
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Regulation of gene expression by micrornas : targeting specificity, kinetics and function [PDF]
, 2011 Summary: Understanding gene regulation is a central question of molecular biology. For decades, gene expression was thought to be controlled by a complex network of proteins called transcription factors.
Hausser, Jean Albert René
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Zhongliu Fangzhi Yanjiu, 2020 Objective To construct a risk model for predicting the prognosis of papillary thyroid carcinoma (PTC) patients based on the expression of microRNAs (miRNA).
JIAO Zhaoshuang, ZHANG Huainian
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Circulating microRNA, secreted microRNA and exogenous plant microRNA [PDF]
Journal of Translational Medicine, 2012 Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves and horses.
openaire +1 more source
MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]
, 2014 Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA +13 more
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MicroRNA-145-5p Regulates the Epithelial-Mesenchymal Transition in Nasal Polyps by Targeting Smad3 [PDF]
Clinical and Experimental OtorhinolaryngologyObjectives. The annual prevalence of chronic rhinosinusitis (CRS) is increasing, and the lack of effective treatments imposes a substantial burden on both patients and society.
Mengyu Zhang +8 more
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miRNAs as Interconnectors between Obesity and Cancer
Non-Coding RNAObesity and cancer are a concern of global interest. It is proven that obesity may trigger the development or progression of some types of cancer; however, the connection by non-coding RNAs has not been totally explored. In the present review, we discuss
Grecia Denisse González-Sánchez +4 more
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