In silico screening of differentially expressed genes influenced by AFAP1-AS1 in lung adenocarcinoma [PDF]
Cellular, Molecular and Biomedical ReportsLong noncoding RNAs (lncRNAs) have regulatory effects on gene expression. Dysregulation of lncRNAs has an essential impact on the transcriptome, influencing cellular functions and behaviors. High expression of lncRNA AFAP1-AS1 has been widely reported in
Zohreh Jahanafrooz, Mahsa Tooshi
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The Role of HSA21 Encoded Mirna in Down Syndrome Pathophysiology:Opportunities in miRNA-Targeted Pharmacotherapy and Diagnosis of the Down Syndrome [PDF]
Pharmaceutical Sciences, 2021 Trisomy 21 is the most prevalent aneuploidy disorder among live-born children worldwide. Itresults from the presence of an extra copy of chromosome 21 which leads to a wide spectrum ofpathophysiological abnormalities and intellectual disabilities ...
Shabnam Mahernia +3 more
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Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. [PDF]
, 2015 Mice in which lung epithelial cells can be induced to express an oncogenic Kras(G12D) develop lung adenocarcinomas in a manner analogous to humans. A myriad of genetic changes accompany lung adenocarcinomas, many of which are poorly understood.
Caswell, DR +11 more
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Bioinformatics study of the role of micro RNAs bta-mir-146a, bta-mir-223, bta-mir 21-5p, bta-mir-181 and bta-mir-16a in the cellular signaling pathways of mastitis in dairy cows [PDF]
مجله بیوتکنولوژی کشاورزی, 2019 Objective It is reasonable to investigate the signaling pathways in diseases such as mastitis in dairy cattle, which are more likely to be affected by epigenetics.
مصطفی قادری +4 more
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A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons [PDF]
, 2018 Mutations in fused in sarcoma (FUS) cause amyotrophic lateral sclerosis (ALS). FUS is a multifunctional protein involved in the biogenesis and activity of several types of RNAs, and its role in the pathogenesis of ALS may involve both direct effects of
Biscarini, Silvia +10 more
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Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]
, 2017 Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma +59 more
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Journal of Research in Medical Sciences, 2020 Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with growing prevalence and increasing economic burden. Based on the role of genetics and epigenetic factors on T2DM, we aimed to carry a systematic review and meta-analysis for all ...
Morteza Gholami +7 more
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MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs [PDF]
, 2016 Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers.
Alfano, Vincenzo +13 more
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生物医学转化, 2022 Sarcopenia is an age-related disease characterized by decreased skeletal muscle quality and function, which seriously affects the quality of life. In recent years, there have been a lot of studies on pathogenesis of sarcopenia and found many application ...
Zhang Wendian
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Detection of MicroRNAs in Dried Serum Blots [PDF]
, 2010 MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Reema Mallick +2 more
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