MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs [PDF]
, 2016 Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers.
Alfano, Vincenzo +13 more
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Nucleic Acids Research, 2004 The miRNA Registry provides a service for the assignment of miRNA gene names prior to publication. A comprehensive and searchable database of published miRNA sequences is accessible via a web interface (http://www.sanger.ac.uk/Software/Rfam/mirna/), and all sequence and annotation data are freely available for download.
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Molecular Oncology, 2012 With the advent of next generation sequencing techniques a previously unknown world of non‐coding RNA molecules have been discovered. Non‐coding RNA transcripts likely outnumber the group of protein coding sequences and hold promise of many new discoveries and mechanistic explanations for essential biological phenomena and pathologies.
Jansson, Martin D, Lund, Anders H
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Study of microRNAs-21/221 as potential breast cancer biomarkers in Egyptian women [PDF]
, 2016 microRNAs (miRNAs) play an important role in cancer prognosis. They are small molecules, approximately 17–25 nucleotides in length, and their high stability in human serum supports their use as novel diagnostic biomarkers of cancer and other pathological
El Masry, Maha Rafik +4 more
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The Predictive Role of MicroRNA19-b in Myocardial Infarction in Rat [PDF]
Journal of Cardio-Thoracic MedicineIntroduction: Cardiovascular disease is one of the leading causes of death worldwide. Acute myocardial infarction (AMI) is the most common and deadly disease of all types of cardiovascular disease.
Danial Falizkaran Yazdi +9 more
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Effect of miRs-17/20 on vasospasm in subarachnoid hemorrhage model of rats
Acta Medica Alanya, 2022 Aim: To investigate the effects of melatonin and miRNA-17/20 administration on vasospasm and vascular damage on the bacillary artery in the Subarachnoid hemorrhage (SAH) model of rats.Methods: Rats were divided into 6 groups: Sham, SAH, SAH+NegmiRNA, SAH+
Ümit Ali Malçok, Başak Büyük
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Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation [PDF]
, 2016 Brain endothelial cells constitute the major cellular element of the highly specialized blood–brain barrier (BBB) and thereby contribute to CNS homeostasis by restricting entry of circulating leukocytes and blood-borne molecules into the CNS.
Arie Reijerkerk +6 more
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Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation [PDF]
, 2010 Acute myeloid leukemia (AML) involves a block in terminal differentiation of the myeloid lineage and uncontrolled proliferation of a progenitor state. Using phorbol myristate acetate (PMA), it is possible to overcome this block in THP-1 cells (an M5-AML ...
A Astrinidis +51 more
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In silico screening of differentially expressed genes influenced by AFAP1-AS1 in lung adenocarcinoma [PDF]
Cellular, Molecular and Biomedical ReportsLong noncoding RNAs (lncRNAs) have regulatory effects on gene expression. Dysregulation of lncRNAs has an essential impact on the transcriptome, influencing cellular functions and behaviors. High expression of lncRNA AFAP1-AS1 has been widely reported in
Zohreh Jahanafrooz, Mahsa Tooshi
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The Role of HSA21 Encoded Mirna in Down Syndrome Pathophysiology:Opportunities in miRNA-Targeted Pharmacotherapy and Diagnosis of the Down Syndrome [PDF]
Pharmaceutical Sciences, 2021 Trisomy 21 is the most prevalent aneuploidy disorder among live-born children worldwide. Itresults from the presence of an extra copy of chromosome 21 which leads to a wide spectrum ofpathophysiological abnormalities and intellectual disabilities ...
Shabnam Mahernia +3 more
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