Results 41 to 50 of about 282,884 (301)

Pre-microRNA and Mature microRNA in Human Mitochondria

open access: yesPLoS ONE, 2011
Because of the central functions of the mitochondria in providing metabolic energy and initiating apoptosis on one hand and the role that microRNA (miRNA) play in gene expression, we hypothesized that some miRNA could be present in the mitochondria for post-transcriptomic regulation by RNA interference.
Barrey, Eric   +5 more
openaire   +5 more sources

Investigating the Expression level of miRNA-21, miRNA-155, miRNA-182, and miRNA-437 along with Inflammatory Markers in Cerebrospinal Fluid of Patients with Multiple Sclerosis

open access: yesJournal of Ardabil University of Medical Sciences, 2022
Background & objectives: Evidence suggests that microRNAs (miRNAs) are essential for immune cell differentiation and function. In addition, miRNAs play an essential role in regulating the expression of pro-inflammatory genes in neurons.
Behrouz Shademan   +5 more
doaj  

Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]

open access: yes, 2011
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M   +60 more
core   +1 more source

Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients [PDF]

open access: yes, 2013
Exosomes are cellular secretory vesicles containing microRNAs (miRNAs). Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell.
Andrea Schmitt   +49 more
core   +1 more source

Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands. [PDF]

open access: yes, 2010
Micro (mi)RNAs are small non-coding RNAs that regulate the expression of their targets' messenger RNAs through both translational inhibition and regulation of target RNA stability.
Marcinowski, Lisa   +53 more
core   +1 more source

The Non-Canonical Aspects of MicroRNAs: Many Roads to Gene Regulation

open access: yesCells, 2019
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently deregulated in many human diseases, including cancer and immunological disorders, it is important to understand their biological functions.
Christiaan J. Stavast   +1 more
doaj   +1 more source

Epigenetics and MicroRNAs [PDF]

open access: yesPediatric Research, 2007
MicroRNAs (miRNAs) regulate protein-coding genes post transcriptionally in higher eukaryotes. Argonaute proteins are important in miRNA regulation and are also implicated in epigenetic mechanisms such as histone modifications and DNA methylation. Here, we review miRNA regulation and outline its connections to epigenetics.
Pål, Saetrom   +2 more
openaire   +2 more sources

Detection of MicroRNAs in Dried Serum Blots [PDF]

open access: yes, 2010
MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Santosh K. Patnaik   +2 more
core  

Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]

open access: yes, 2010
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri   +23 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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