Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. [PDF]
, 2015 Mice in which lung epithelial cells can be induced to express an oncogenic Kras(G12D) develop lung adenocarcinomas in a manner analogous to humans. A myriad of genetic changes accompany lung adenocarcinomas, many of which are poorly understood.
Caswell, DR +11 more
core +2 more sources
Bioinformatics study of the role of micro RNAs bta-mir-146a, bta-mir-223, bta-mir 21-5p, bta-mir-181 and bta-mir-16a in the cellular signaling pathways of mastitis in dairy cows [PDF]
مجله بیوتکنولوژی کشاورزی, 2019 Objective It is reasonable to investigate the signaling pathways in diseases such as mastitis in dairy cattle, which are more likely to be affected by epigenetics.
مصطفی قادری +4 more
doaj +1 more source
Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [PDF]
, 2015 Background: Clinical decision and patient care management in inflammatory bowel diseases is largely based on the assessment of clinical symptoms, while the biomarkers currently in use poorly reflect the actual disease activity.
Alexandra Touroutoglou +31 more
core +1 more source
MicroRNAs in melanoma development and resistance to target therapy [PDF]
, 2017 microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio +7 more
core +1 more source
Journal of Research in Medical Sciences, 2020 Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with growing prevalence and increasing economic burden. Based on the role of genetics and epigenetic factors on T2DM, we aimed to carry a systematic review and meta-analysis for all ...
Morteza Gholami +7 more
doaj +1 more source
Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]
, 2015 Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A +7 more
core +2 more sources
Circulating microRNA, secreted microRNA and exogenous plant microRNA [PDF]
Journal of Translational Medicine, 2012 Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves and horses.
openaire +1 more source
生物医学转化, 2022 Sarcopenia is an age-related disease characterized by decreased skeletal muscle quality and function, which seriously affects the quality of life. In recent years, there have been a lot of studies on pathogenesis of sarcopenia and found many application ...
Zhang Wendian
doaj +1 more source
miRNAs as Interconnectors between Obesity and Cancer
Non-Coding RNAObesity and cancer are a concern of global interest. It is proven that obesity may trigger the development or progression of some types of cancer; however, the connection by non-coding RNAs has not been totally explored. In the present review, we discuss
Grecia Denisse González-Sánchez +4 more
doaj +1 more source
Journal of Natural Fibers, 2022 Flax fiber was one of the earliest natural fibers utilized by humans. Current research on flax fiber development is mainly focused on functions of key genes, with few reports investigating regulation of microRNA expression.
Ying Yu +7 more
doaj +1 more source