Results 51 to 60 of about 360,741 (311)

Loss of miR-107, miR-181c and miR-29a-3p promote activation of Notch2 signaling in pediatric high-grade gliomas (pHGGs) [PDF]

, 2017
The mechanisms by which microRNAs control pediatric high-grade gliomas (pHGGs) have yet to be fully elucidated. Our studies of patient-derived pHGG tissues and of the pHGG cell line KNS42 revealed down-regulation in these tumors of three microRNAs ...
Abballe, Luana, Antonelli, Manila, Bellavia, Diana, Besharat, Zein Mersini, Catanzaro, Giuseppina, Chiacchiarini, Martina, Ferretti, Elisabetta, Gessi, Marco, Giangaspero, Felice, Locatelli, Franco, Mastronuzzi, Angela, Miele, Evelina, Napolitano, Maddalena, Peruzzi, Giovanna, Po, Agnese, Rosa, Alessandro, Russo, Michele, Sabato, Claudia, Screpanti, Isabella, Vacca, Alessandra   +19 more
core   +2 more sources

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria, Laface, Ilaria, Milani, Daniela, Neri, Luca M, Rimondi, Erika, Simioni, Carolina, Varano, Gabriele   +6 more
core   +1 more source

Pre-microRNA and Mature microRNA in Human Mitochondria

PLoS ONE, 2011
Because of the central functions of the mitochondria in providing metabolic energy and initiating apoptosis on one hand and the role that microRNA (miRNA) play in gene expression, we hypothesized that some miRNA could be present in the mitochondria for post-transcriptomic regulation by RNA interference.
Barrey, Eric, Saint-Auret, Gaelle, Bonnamy, Blandine, Damas, Dominique, Boyer, Orane, Gidrol, Xavier   +5 more
openaire   +5 more sources

microRNAs: Novel regulators of the TGF-β pathway in pancreatic ductal adenocarcinoma

Molecular & Cellular Oncology, 2018
We identified that transforming growth factor-β (TGF-β) induces long non-coding RNA (lncRNA) MIR100HG along with its host microRNAs (miRNAs) miR-100 and miR-125b, to regulate its response in pancreatic ductal adenocarcinoma (PDAC).
Silvia Ottaviani, Leandro Castellano
doaj   +1 more source

Detection of MicroRNAs in Dried Serum Blots [PDF]

, 2010
MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Reema Mallick, Sai Yendamuri, Santosh K. Patnaik   +2 more
core   +2 more sources

Expression of microRNA-31 and microRNA-205 in basal cell carcinoma, squamous cell carcinoma, and healthy controls: a comparative study

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background MicroRNAs (miRNAs) are small nonprotein coding RNAs that play an important role in physiological cellular processes. MicroRNA (miR)-205 and miR-31 are among the most frequently altered miRNAs in human malignancies. Objective To measure miR-205
Hanan R Nada, Eman A El-Nabarawy, Sara B Mahmoud, Yasmin A Emara, Laila A Rashed   +4 more
doaj   +1 more source

Research progress on the regulation of malignant biological behavior of glioma by miRNA-145

Chinese Journal of Contemporary Neurology and Neurosurgery
Glioma is the most malignant brain tumor with high mortality. Due to its complex biological characteristics such as malignant proliferation, invasion, drug resistance, and immunosuppression, the clinical treatment faces great difficulties.
WANG Jun-cheng, LI Xin-long, MA Dong-ming, PAN Ya-wen   +3 more
doaj   +1 more source

Protective Effect of Alginate Extraction of Brown Algae on MicroRNAs in Type 1 Diabetes of Rats [PDF]

International Journal of Nutrition Sciences
Background: MicroRNAs expressions that are known as Posttranscriptional repressors of gene expression in animals and plants have an important role in diabetic consequences and pathogenesis.
Mohammad Sharifzadeh, Aghil Esmaeili-Bandboni, Mohammadreza Emami, Abbas Mirshafiey, Mohammad Hassan Javanbakht   +4 more
doaj   +1 more source

Evaluation of the expressed miR-129 and miR-549a in patients with multiple sclerosis

Advanced Biomedical Research, 2021
Background: The expression of microRNAs (miRNAs) as circulating biomarkers has been underlined in multiple sclerosis (MS) in the last decade. Due to the presence of a possible relationship between expressed miRNAs and heterogeneous appearances of the ...
Mina Montazeri, Nahid Eskandari, Reza Mansouri   +2 more
doaj   +1 more source

MicroRNAs in lung cancer [PDF]

, 2017
Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this ...
An, Baltimore, Belinsky, Brennan, Chen, De Flora, De Flora, Dong, Duan, Gomez, Hao, Harris, Hasegawa, Haugen, Hu, Inoue, Jemal, Jia, Lam, Li, Liu, Nakanishi, Neilson, O'Driscoll, Pan, Peiper, Ren, Schmeck, Schrump, Sensinger, Shah, Slack, Speiser, Stampfli, Wang, Wang, Yoshida, You, Zhang, Zhang, Zienolddiny   +40 more
core   +1 more source