Results 61 to 70 of about 360,741 (311)
The AAPS Journal, 2010 MicroRNAs (miRNAs), a class of small, regulatory, non-coding RNA molecules, display aberrant expression patterns and functional abnormalities in human diseases including cancers. This review summarizes the abnormally expressed miRNAs in various types of human cancers, possible mechanisms underlying such abnormalities, and miRNA-modulated molecular ...
Mengfeng, Li +4 more
openaire +2 more sources
Exploring Epigenetic Mechanisms in Aggressive Periodontitis; Unraveling the Molecular Dynamics of Disease Progression: A Narrative Review [PDF]
Iranian Journal of Medical SciencesAggressive periodontitis is an inflammation of the periodontal tissue that usually affects adolescents and young adults aged
Ranny Grevanny +3 more
doaj +1 more source
Molecular medicine of microRNAs: structure, function and implications for diabetes [PDF]
, 2008 MicroRNAs (miRNAs) are a family of endogenous small noncoding RNA molecules, of 19–28 nucleotides in length. In humans, up to 3% of all genes are estimated to encode these evolutionarily conserved sequences.
Duncan +5 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
International Journal of Nephrology and Renovascular Disease, 2020 Seyyedeh Mina Hejazian,1– 3 Mohammadreza Ardalan,2 Mohammadali M Shoja,4 Nasser Samadi,1 Sepideh Zununi Vahed2 1Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran; 2Kidney ...
Hejazian SM +4 more
doaj
Expression of miRNA-25 in young and old lung adenocarcinoma
Journal of Research in Medical Sciences, 2021 Background: An appropriate personalized molecular testing ensures the most efficacious treatment in lung cancer. It is still controversial whether younger lung adenocarcinoma (LUAD) patients have different molecular features compared with their older ...
Laura Boldrini +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
MiRNA-Based Inspired Approach in Diagnosis of Prostate Cancer
Medicina, 2020 Prostate cancer is one of the most encountered cancer diseases in men worldwide and in consequence it requires the improvement of therapeutic strategies. For the clinical diagnosis, the standard approach is represented by solid biopsy.
Vlad Cristian Munteanu +5 more
doaj +1 more source
Role of exosomal miRNAs in brain metastasis affected by radiotherapy
Translational Neuroscience, 2021 In oncogenesis and development of malignant tumor, microRNAs (miRNAs) regulate the complex gene expression associated with the tumor pathogenesis. Currently, only few studies have been conducted to identify miRNAs and the potential pathways involved in ...
Li Zihuang +4 more
doaj +1 more source
microRNA. Diagnostic Perspective [PDF]
, 2015 Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core +2 more sources