Results 61 to 70 of about 282,884 (301)

Transcriptomic profile assessment for preeclampsia prediction and early diagnostics

open access: yesАкушерство, гинекология и репродукция
Aim: to develop a model for predicting preeclampsia (PE) based on the clinically most significant differentially expressed plasma microRNAs.Materials and Methods. A prospective observational comparative study was conducted with 62 women, divided into two
A. V. Melnik   +14 more
doaj   +1 more source

CHO microRNA engineering is growing up : recent successes and future challenges [PDF]

open access: yes, 2013
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes   +12 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway

open access: yesActa Pharmaceutica, 2020
Curcumin has been proved to inhibit cell proliferation and induce cell apoptosis in non-small cell lung cancer (NSCLC). However, little is known about antimetastatic effects and molecular mechanisms of curcumin in NSCLC.
Wang Naizhi   +3 more
doaj   +1 more source

MicroRNA Expression Profiles of Epicardial Adipose Tissue-Derived Exosomes in Patients with Coronary Atherosclerosis

open access: yesReviews in Cardiovascular Medicine, 2022
Background and Aims: Epicardial adipose tissue, exosomes, and miRNAs have important activities in atherosclerosis. The purpose of this study was to establish miRNA expression profiles of epicardial adipose tissue-derived exosomes in patients with ...
Jinxing Liu   +17 more
doaj   +1 more source

MicroRNA-34, microRNA-130, microRNA-148, microRNA-181, microRNA-194 and microRNA-605 expression in colon cancer tissue

open access: yesSouth Russian Journal of Cancer
Purpose of the study. Determination of the expression of microRNA‑34, microRNA‑130, microRNA‑148, microRNA‑181, microRNA‑194 and microRNA‑605 in colon tumor tissue depending on the clinical and morphological features of the tumor and the effectiveness of treatment.Materials and methods.
D. I. Azovsky   +6 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The copper microRNAs [PDF]

open access: yesNew Phytologist, 2016
SummaryCopper (Cu) microRNAs are upregulated by Cu deficiency and mediate the post‐transcriptional downregulation of transcripts that encode Cu proteins, suggesting a role directly related to Cu. However, expression and phenotypic analyses of copper microRNA mutants and over‐expressors have suggested roles mainly in tolerance to abiotic stresses.
openaire   +2 more sources

Mammalian cells in culture actively export specific microRNAs [PDF]

open access: yes, 2009
The discovery of microRNAs (miRNAs) as a new class of regulators of gene expression has triggered an explosion of research, but has left many unanswered questions about how this regulation works and how it is integrated with other regulatory mechanisms ...
David J. Galas   +4 more
core  

MicroRNAs in Diffuse Large B-Cell Lymphoma

open access: yes, 2013
Diffuse large B‐cell lymphoma (DLBCL), the most common sub‐type of non‐Hodgkin's lymphomas (NHL), is a genetically and clinically heterogeneous disease.
Alencar, Alvaro J   +3 more
core   +1 more source

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