Results 81 to 90 of about 97,236 (208)
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang +13 more
wiley +1 more source
Diagnostic Value of Combining miRNAs, CEA Measurement and the FOBT in Colorectal Cancer Screening
Cancer Management and Research, 2020 Xiaodan Li,1 Rong Chen,2 Zhifa Li,2 Bing Luo,1 Wenyan Geng,1 Xiaobing Wu2 1Clinical Laboratory, The Third Affiliated Hospital of the Guangzhou Medical University, Guangzhou 510150, People’s Republic of China; 2Gastrointestinal Surgery, The Third ...
Li X, Chen R, Li Z, Luo B, Geng W, Wu X
doaj
Advanced Science, EarlyView.The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang +12 more
wiley +1 more source
RNAi and retroviruses: are they in RISC?
Biomolecular Concepts, 2013 RNA interference (RNAi) is a potent cellular system against viruses in various organisms. Although common traits are observed in plants, insects, and nematodes, the situation observed in mammals appears more complex.
Vasselon Thierry +3 more
doaj +1 more source
Exosomal microRNAs as potential biomarkers in pediatric Burkitt Lymphoma
, 2022 reservedBurkitt Lymphoma (BL) is a highly aggressive B-cell non Hodgkin lymphoma. It is the most frequent subtype of NHL in children and adolescents, accounting for 38% of patients from 0 to 14 years old. The current recommended approach of diagnosis and
RIZZATO, DOMENICO
core
Advanced Science, EarlyView.Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong +5 more
wiley +1 more source
Romanian Journal of Laboratory Medicine, 2016 The management of the critically ill polytrauma patient is complex due to the multiple complications and biochemical and physiopathological imbalances. This happened due to the direct traumatic injury, or due to the post-traumatic events. One of the most
Bedreag Ovidiu Horea +8 more
doaj +1 more source
Novel mature microRNAs derived from known microRNA precursors (pre-microRNAs).
, 2012 Novel mature microRNAs derived from known microRNA precursors (pre-microRNAs).
Hélène Plé (114528) +5 more
core +1 more source